Objective To investigate the prevalence of asthma in children aged 3 to 14 years in Lianyungang. Methods A total of 9 612 children were selected by distributed cluster random sampling and investigated by screening questionnaire.The Results were statistically analyzed by SPSS 19.0. Results The prevalence of asthma among children aged 3 to 14 in Lianyungang city was about 4.2%.The prevalence rate of male was about 5.01% and the prevalence rate was about 3.28%.Weather change or exposure to cold air was the main cause of asthma exacerbation in children in this region.Synthetic board furniture was given priority to asthma group and prevalence of father smoking was significantly greater than the control group (P<0.05).The utilization rate of β-lactam antibiotics before asthma diagnosis was 80.60%.Only 47.01% of families indicated that they were fully able to bear the cost of treatment.33.58% of children indicated that asthma affected their learning time more than 10 days each year,and 5.97% of the children never participated in sports activities. Conclusions The prevalence of asthma in children aged 3 to 14 years old in Lianyungang is higher than that of the national average prevalence.The improvement of living environment and style,timely diagnosis,rational use of drugs and standard treatment are keys to prevention and control of asthma.