Objective To investigate the effect of health education path in children's early education,in order to seek effective Methods for infant education. Methods In March 2014,65 infants aged 30~42 days receired physical examination in children health care clinic of the Second Affiliated Hospital of Xinjiang Medical University were selected according to selection criteria,who were divided into the intervention group (34 cases) and the control group (31 cases),early education related content training was implemented according to the health education path in the intervention group,while controversial health education was implemented in the control group.Two groups were not participated in any early education institutions.Two groups over 1 year of age were testing of the development quotient,weight and height and the incidence of common diseases and the evaluation of the effect. Results The adaptability,fine motor and personal social with intervention group were higher than those of the control group 6 points or so;The big movement and language were higher than those of the control group(about 11 points),the differences were statistically significant (P<0.05).There was no significant difference in weight and height between the two groups (P>0.05).The incidence rate of common disease with the intervention group was less than the control group (P<0.05). Conclusion The application of health education pathway in early childhood education can effectively improve the mental development of infants,reduce the incidence of common diseases,and is worth to be popularized.