Objective To understand the present situation of infantile eczema,and to explore the influencing factors of infantile eczema. Methods According to the principle of "informed consent and voluntary",a total of 1 135 infants,at the age of 1 month,6 months and 12 months,were selected randomly from Suzhou Municipal Hospital from March to September 2016.The questionnaires were conducted to infants′ parents,recording the potential related factors of infantile eczema.Chi-square test and Logistic regression analysis were used to analyze the related factors of infantile eczema. Results 1) The prevalence rates of infantile eczema at the age of 1 month,6 months and 12 months old were 59.1%,41.7% and 19.8% respectively with significant difference(P<0.05).2) Single factor analysis showed that infantile eczema was related to feeding pattern,baby care products and outdoor activity time (P＜0.05).Logistic regression analysis showed that artificial feeding (OR=2.695,95% CI:1.826-3.976) and mixed feeding (OR=1.530,95% CI:1.179-1.986) were risk factors of infantile eczema(P<0.01).Outdoor activities for 1 to 2 hours (OR=0.475,95% CI:0.343-0.658),outdoor activities for more than 2 hours (OR=0.273,95% CI:0.162-0.460) and the use of baby care products (OR=0.755,95% CI:0.592-0.964) were protective factors of infantile eczema(P<0.05). Conclusions 1) The prevalence of infantile eczema decreases with age,and the balance of Th1/Th2 tends to ease eczema.2) Breastfeeding,appropriate outdoor activities and usage of proper baby care products may reduce the occurrence of infantile eczema.