Objective To analyze the secular growth trend and nutrition status among the Li'su ethnicity children and adolescents in China from 2005 to 2014,and supply the suggestions to improve their growth and nutrition. Methods From 2005 to 2014,the children and adolescents from 24 primary and secondary school of 3 counties of Yunnan Nujiang Prefectures aged 7 to 18 were enrolled for the physic examination with the multistage stratified random cluster sampling.Using WHO-2006 standard,the changes of the rate of the students' growth retardation and malnutrition were compared,the students' secular growth and nutrition development trends were analyzed from 2005 to 2014 in the national student physical health research students. Results The malnutrition rate of Li'su boys and girls were respectively decreased from 48.84% and 41.13% to 30.96% and 23.41%.The rate of 7~18 years old Li'su boys growth retardation in 2005,2010 and 2014 were respectively 43.22%,35.54% and 25.80%;The rate of 7~18 years old Li'su girls growth retardation were respectively 38.15%,33.56% and 20.30%.The sex difference of 18-year-old height were respectively 8.94 cm,9.96 cm and 11.28 cm in 2005,2010 and 2014. Conclusions The nutritional status of Li'su children and adolescents has been significantly improved,but malnutrition remains a serious public health problem.For the serious malnutrition phenomenon,and the sex difference of height was less than 13cm.The intervention of nutrition and health education were recommended to carry on and further promote and facilitate the Students' Nutrition Improvement Program,and to develop the height growth potential of Li'su students.