Objective To evaluate the clinical characteristics of neonatal sepsis in preterm and term infants. Methods A total of 97 preterm and 43 term neonatal sepsis were retrospectively analyzed. Results Early-onset sepsis was higher in preterm neonatal sepsis than that in term neonatal sepsis (P<0.01).Conversely,late-onset sepsis was higher in term neonatal sepsis than that in preterm neonatal sepsis (P<0.01).Comparing with term neonatal sepsis,preterm neonatal sepsis tended more to accompany premature rupture of membranes,caesarean section,PICC catheterization,umbilical vein catheterization and intravenous nutrition (all P<0.01).Possibilities of mother perinatal infection,meconium-stained amniotic fluid and natural labor in term neonatal sepsis were higher than those in preterm neonatal sepsis (all P<0.01).Preterm neonatal sepsis tended to have low response,feeding intolerance,abdominal distension,apnea,dyspnea and ventilation treatment (all P<0.05 or <0.01).Term neonatal sepsis tended to have abnormal temperature,pathologic jaundice and skin infection (all P<0.01).Preterm neonatal sepsis was susceptible to complicate with infectious shock and neonatal necrotizing enterocolitis (P<0.01,<0.05).Their white blood cells and platelet obviously decreased (all P<0.01). Conclusions Sepsis in preterm and term infants is somewhat different in clinical manifestations and laboratory tests.Preterm neonatal sepsis often involves multiple systemic changes.
Key words
neonatal sepsis /
term infant /
preterm infant
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