Objective To investigate the physical,motor and intelligent development trend of premature infants of different ages until 24 months old,and to provide a basic theory for early intervening premature infants. Methods A total of 82 premature infants were divided into two groups (more than or equal to 32 weeks in late preterm infants group and less than 32 weeks in early preterm infants group),and followed up regularly.The premature infants' physical,motor and intelligent developments were assessed at 6,12,18,24 corrected months. Results 1)Physical development had statistically differences between two groups at 6 months of age on weight,length and head circumference.The weight component ratio difference was continued until to corrected age of 12 months.2)Psychomotor developmental index (PDI) of two groups in corrected age of 6 and 12 months were significantly less than 85 points,and the gap to 85 points of early preterm group was bigger,while both of them were up to 85 or more points without correction at 18 months corrected age.3)Mental developmental index (MDI) of two groups in corrected age of 6,12 and 18 months were significantly less than 85 points,and the gap to 85 points of early preterm group was bigger,while both of them were up to 85 or more points without correction at 24 months corrected age. Conclusions Catch-up growth of early preterm infants within a year was not enough and the weight is outstanding.It recommends strengthening early fortified group of preterm infants.Motor and intelligence development level in the two groups within corrected age of 24 months was obviously lower than children of the same age,and they can catch up with children of the same age at the corrected age of 24 months.Motor and intelligence development of premature infants in two groups showed a catch-up development trend within corrected age of 24 months.