Objective To study the primary enuresis (PNE) in children's psychological and behavioral problems and related factors,and to provide reference for clinical psychological intervention and treatment aged 6 to 11. Methods Using cross sectional design,72 cases of PNE children aged 6 to 11 were selected from Boai Hospital from June 2013 to June 2015 as observation group;At the same time,82 cases of children aged 6 to 11 who participated in physical examination were selected as control group.Their psychological behavior problems were measured by Achenbach Child Behavior Scale (CBCL),while self-designed questionnaires were used to collect general data.The each factor scores of CBCL were compared between two groups.The PNE children's psychological behavior problems and related factors were analyzed. Results For boys,except hyperactivity and discipline,the other factors' scores of the observation group were higher than those of control group (P<0.05);For girls,in addition to schizophrenia,hyperactivity and discipline,other factor's scores of the observation group were higher than those of control group (P<0.05).CBCL behavior problems detection rate (34.72%) of the observation group was obviously higher than that of control group (7.32%),with statistically significant difference (χ²=18.541,P=18.541).Children whose age older,parents relationship worse,nocturia children raised by olders or a nanny,had higher CBCL total score,and the serious psychological behavior problems.Children with parents education higher,the family main parenting was democratic or hybrid,had lower CBCL total score,so they were protective factors. Conclusions Primary enuresis children aged 6 to 11 have adverse psychological behavior problems such as depression,social withdrawal.They are associated with age and parents' education.So combined with the related factors,such measures as a good family environment should be created to strengthen the psychological intervention treatment.