Objective To explore correlation between vitamin D with fasting plasma insulin,C-Peptide and blood glucose. Method The concentrations of serum 25-hydroxyvitamin D2[25(OH)D2],25-hydroxycholecalciferol[25(OH)D3],25-hydroxyvitamin D[25(OH)D],fasting plasma insulin(INS),C-Peptide(CP)and blood glucose (GLU) were measured in 58 full-term infants and 42 preterm infants,and the data were statistically analyzed by SPSS 17.0 software. Results The 25(OH)D3,25(OH)D,INS,CP and GLU in group of full-term infants were higher than those in group of preterm infants(P<0.05).Levels of serum 25(OH)D3,25(OH)D in full-term infants had positive correlations with INS,CP (r=0.515,0.324,0.523,0.335,P＜0.05 or <0.01),and negative correlations with GLU(r=-0.489,-0.514,all P＜0.01).Levels of serum 25(OH)D3,25(OH)D in preterm infants had positive correlations with INS,CP (r=0.509,0.367,0.598,0.432,P<0.05 or ＜0.01),and negative correlations with GLU(r=-0.539,-0.587,all P＜0.01). Conclusion Levels of serum 25-hydroxyvitamin D in neonates have positive correlations with fasting plasma insulin and C-Peptide,and negative correlations with blood glucose.
Key words
neonate /
full-term infant /
preterm infant /
vitamin D /
insulin /
C-Peptide /
blood glucose
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