Objective To explore a new mode to improve screening compliance in hearing screening. Method A total of 956 patients undergoing failed in hearing screening of newborns,were randomly divided into Intervention group and control group,the intervention group used "Health education-education information dissemination-mobile phone SMS booking-call notification" mode back to the hospital screening before intervention;the control group was divided into fore groups,group 1 of health education,group 2 of releasing related information,group 3 of mobile phone SMS booking,group 4 of telephone notification;statistics of five groups of screening rate,gender,the living condition and the guardian education level,results were statistically analyzed. Results Screening rate of the intervention group was 92.75%,screening rates of four control group were 65.08%,57.07%,78.24%,83.68%,respectively.There were significant differences between intervention group and control group (P<0.05),and there were no significant differences in the gender,the living condition and the guardian education level of the groups (P>0.05). Conclusion To improve the hearing screening compliance is necessary,and the application of "Health Education-education information dissemination-mobile phone SMS booking-call notification" combination mode is effect to improve the screening compliance than single mode.