Objective To explore the prevalence,diagnosis and management of childhood asthma in Lanzhou urban area. Methods Multi-stage,stratified and random cluster sampling was used to recruit children born during July 1st,1996 to July 1st,2010 from Lanzhou or other provinces but resided in Lanzhou for over half a year.The same screening questionnaires for the Third National Epidemiological Survey of Children's Asthma were distributed to parents of children at schools,kindergartens and communities.Asthmatic children were picked among the screening-positive children based on on-the-spot inquiries,physical examinations,medical records and supporting test results.Further survey of asthmatics was carried out to investigate the diagnosis and treatment status of childhood asthma and other associated allergic diseases.All data required double entry by Epi-Info 3.5.3 software and were processed by SPSS 19.0. Results Among a total of 11 068 questionnaires,10 566 were completed with a response rate of 95.46%.And 298(2.82%) children were diagnosed with typical (n=265,2.51%) and cough variant (n=33,0.31%) asthma.Among them,54.36%(162/298) had been previously diagnosed with asthma.The prevalence of asthma was higher in boys than in girls [3.31%(180/5 440) vs 2.30%(118/5 126),χ2=9.761,P<0.01].The asthma prevalence of preschoolers (3～<7 years old) was the highest (4.31%(116/2 690)).In the past two years,the symptoms of 84.90% (253/298) children persisted and the current two-year prevalence of asthma was 2.39% (253/10 566).Among the 162 children with previous asthma,87.65% (142/162) received inhaled corticosteroids according to the Global Initiative for Asthma (GINA) and 87.04%(141/162) of them used antibiotics. Conclusions The prevalence of asthma is 2.82% in children under 14 years old in Lanzhou urban area,increased significantly over the past ten years,and it varied in children with different genders and ages.A considerable number of children are not diagnosed or treated properly,and the management of asthma requires further improvement.
Key words
child /
asthma /
prevalence
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References
[1] The Global Initiative For Asthma.Pocket guide for asthma management and prevention,Global Initiative for Asthma (GINA)2011[EB/OL].(2011-12) [2012-10-15].http://www.ginasthma.org /guidelines-pocket-guide-for-asthma-management.html.
[2] The Global Initiative For Asthma.Global Strategy for the Diagnosis and Management of Asthma in Children 5 Years and Younger.Global Initiative for Asthma (GINA) 2009 [EB/OL].2009 [2012-10-15].http://www.ginasthma.org/guidelines-global-strategy-for-the-diagnosis.html.
[3] Asher I,Pearce N.Global burden of asthma among children[J].Int J Tuberc Lung Dis,2014,18(11):1269-1278.
[4] Anandan C,Nurmatov U,Van Schayck OC,et al.Is the prevalence of asthma declining? Systematic review of epidemiological studies[J].Allergy,2010,65(2):152-167.
[5] 全国儿科哮喘防治协作组.全国90万0～14岁儿童中支气管哮喘患病情况调查[J].中华结核和呼吸杂志,1993,16(Suppl):64-68.
[6] 全国儿童哮喘防治协作组.中国城区儿童哮喘患病率调查[J].中华儿科杂志,2003,41(2):123-127.
[7] 中华医学会儿科学会呼吸学组,《中华儿科杂志》编辑委员会.儿童支气管哮喘诊断与防治指南[J].中华儿科杂志,2008,46(10):745-753.
[8] 陈育智,李元,刘世英,等.北京地区4万儿童哮喘患病情况调查[J].北京医学,1995,17(1):1-4.
[9] 马煜,陈育智,陈再历,等.2000年北京城区儿童哮喘患病情况调查分析[J].北京医学,2002,24(3):173-176.
[10] 沈华浩.哮喘手册[M].2版.北京:人民卫生出版社,2009.
[11] Masoli M,Fabian D,Holt S,et al.The global burden of asthma:executive summary of the GINA Dissemination Committee report[J].Allergy,2004,59(5):469- 478.
[12] 全国儿科哮喘协作组.2000年与1990年儿童支气管哮喘患病率的调查比较[J].中华结核和呼吸杂志,2004,27(2):112-116.
[13] Nishimura KK,Galanter JM,Roth LA,et al.Early life air pollution and asthma risk in minority children:the GALA II & SAGE II studies[J].Am J Respir Crit Care Med,2013,188(3):309-318.
[14] 王次林,王梅,罗荣华,等.成都市城区儿童哮喘流行病学调查[J].中国儿童保健杂志,2003,11(1):32-34.
[15] Shea KM,Truckner RT,Weber RW,et al.Climate change and allergic disease [J].J Allergy Clin Immunol,2008,122(3):443-453.
[16] Postma DS.Gender differences in asthma development and progression[J].Gend Med,2007,4(Suppl B):133-146.
[17] Vercelli D.Genetics and biology of asthma 2010:La'Ci darem la mano[J].J Allergy Clin Immunol,2010,125( 2):347-348.
[18] Ege MJ,Mayer M,Normand AC,et a1.Exposure to environmental microorganisms and childhood asthma[J].N Engl J Med,2011,364(8):701-709.
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