Objective To assess the life quality of the cerebral palsy (CP) children with spasm pain.Methods The method of cross-sectional case-control was used to investigate the life quality of 54 cerebral palsy children with spasm pain and 100 normal children by Pediatric Quality of Life Inventory TM Version 4.0 (PedsQLTM4.0).Results The scores (physical functioning,psychological functioning,emotional functioning,school functioning and total score)of study group were lower than those of the normal group (P<0.05);the scores had no statistical significances between the female and male;the scores of the five part had no statistical significances between 2~4 years old age group,5~7 years old age group and 8~13 years old age group(P>0.05);The scores of physical functioning and psychological functioning of 1~2 level of GMFCS (Gross Motor Function Classification System) were higher than those of the 3~5 level (P<0.05),the scores of other three part had no statistical significances (P>0.05);the score of physical functioning and school functioning had positive correlations with the total score of GMFM-88 (r=0.478,0.413,P<0.05).Conclusion The life quality of the cerebral palsy children with spasm pain is worse than the normal children,and the severity of their life quality has significant correlation with gross motor function.