Objective To seek related genetic pathogenic factors by cytogenetic analysis in 20 infants with fetal growth restriction (FGR).Methods A total of 20 FGR infants were recruited in Wuhan Maternal and Children Health Care Center from January 2012 to June 2014.The samples of the peripheral blood lymphocytes were prepared with routine cytogeneticMethods ,G-banding was employed for karyotype analysis. Result Cytogenetic analysis revealed 10 cases with chromosomal abnormalities,5 cases of Down's syndrome,1 case of Edward's syndrome,4 cases of chromosome structural abnormalities.Conclusion s Chromosome aberrations related to the fetal growth restriction.It is suggested that more chromosomal information of FGR infants should be acquired,it benefits for early management and intervention of genetic diseases.
Key words
fetal growth restriction /
cytogenetics /
infant
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