objective To study the clinical features of food allergy in infant and young children,and to provide the basis for the diagnosis and prevention of this disease. Methods Consecutive infants and young children aged 0～3 years attending at the outpatient department of gastroenterology,children's hospital of Wenzhou,were invited to participate in the study.Parents completed questionnaires,and children detected total serum IgE and serum food specific IgE (cow's milk,egg yolk,egg white,soybean,sea fish,shrimp,crab).Subjects with either a positive food specific IgE or a positive medical history were invited to undergo an food elimination test and followed up of 6 months. Results The total positive rate of food allergy was 18.99% in this study.The most common food allergens were milk (55.56%) and egg (15.56%).The common clinical manifestations of food allergy were mainly eczema and hematochezia. Conclusions The main allergy foods of infant and young children in Wenzhou city are milk,egg white,and the common clinical manifestations of food allergy are mainly of eczema and hematochezia.Food avoidance is an effective measure for treatment of food allergy.