A Correlative study of sleep disturbances and fatigue among children with acute leukemia

BU Xiu-qing; MO Ying-lei; YE Qi-meng; YOU Li-ming

doi:10.11852/zgetbjzz2015-23-06-06

PDF(454 KB)

Chinese Journal of Child Health Care ›› 2015, Vol. 23 ›› Issue (6) : 577-579. DOI: 10.11852/zgetbjzz2015-23-06-06

Original articles

A Correlative study of sleep disturbances and fatigue among children with acute leukemia

BU Xiu-qing¹,MO Ying-lei²,YE Qi-meng³,YOU Li-ming¹

Author information +

History +

Abstract

Objective To explore the correlation of sleep disturbances and fatigue among children with acute leukemia. Methods The main caregivers of 65 children with acute leukemia were surveyed on the Sleep Disturbance Scale for Children (SDSC) and the Pediatric Quality of Life Inventory TM (PedsQL TM) Multidimensional Fatigue Scale (MFS) (Parent Investigation Questionnaire). Results The total score of SDSC scale was (47.83±10.74) on average.The prevalence of sleep disorders of children with acute leukemia was 6.15%.Sleep-wake transition disorders,sleep breathing disorders,and disorders of arousal were the first three common disorders.The total score of PedsQL TMMFS was (60.41±17.26) on average.The ascending order of the three dimensions' score was general fatigue,sleep fatigue and cognitive fatigue.The total score of sleep disturbances was negatively correlated with that of fatigue (r=-0.51,P<0.001),which meaned that the more serious the sleep disturbance was,the more serious the fatigue was. Conclusions The most common sleep disturbances of children with acute leukemia in hospital are sleep-wake transition disorders,sleep breathing disorders,and disorders of arousal.General fatigue and sleep fatigue are the main manifestations of fatigue.Sleep disturbances and fatigue are negatively correlated with each other.

Key words

acute leukemia / sleep disturbances / fatigue / children

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

BU Xiu-qing,MO Ying-lei,YE Qi-meng,YOU Li-ming. A Correlative study of sleep disturbances and fatigue among children with acute leukemia[J]. Chinese Journal of Child Health Care. 2015, 23(6): 577-579 https://doi.org/10.11852/zgetbjzz2015-23-06-06

References

[1] Pui CH,Carroll WL,Meshinchi S,et al.Biology,risk stratification,and therapy of pediatric acute leukemias:an update[J].J Clin Oncol,2011,29(5):551-565.
[2] Hockenberry MJ,Hooke MC,Gregurich M,et al.Symptom clusters in children and adolescents receiving cisplatin,doxorubicin,or ifosfamide[J].Oncol Nurs Forum,2010,37(1):e16-27.
[3] Bruni O,Ottaviano S,Guidetti V,et al.The Sleep Disturbance Scale for Children (SDSC) Construction and validation of an instrument to evaluate sleep disturbances in childhood and adolescence[J].J Sleep Res,1996,5(4):251-261.
[4] Romeo DM,Bruni O,Brogna C,et al.Application of the sleep disturbance scale for children (SDSC) in preschool age[J].Eur J Paediatr Neurol,2013,17(4):374-382.
[5] Huang MM,Qian Z,Wang J,et al.Validation of the Sleep Disturbance Scale for Children and prevalence of parent-reported sleep disorder symptoms in Chinese children[J].Sleep Med,2014,15(8):923-928.
[6] Guillemin F,Bombardier C,Beaton D.Cross-cultural adaptation of health-related quality of life measures:literature review and proposed guidelines[J].J Clin Epidemiol,1993,46(12):1417-1432.
[7] Varni JW,Burwinkle TM,Katz ER,et al.The PedsQL in pediatric cancer:reliability and validity of the Pediatric Quality of Life Inventory Generic Core Scales,Multidimensional Fatigue Scale,and cancer module[J].Cancer,2002,94(7):2090-2106.
[8] Varni JW,Limbers CA,Bryant WP,et al.The PedsQL?Multidimensional Fatigue Scale in pediatric obesity:Feasibility,reliability,and validity[J].International Journal of Pediatric Obesity,2010,5(1):34-42. [9] Panepinto JA,Torres S,Bendo CB,et al.PedsQLim Multidimensional Fatigue Scale in sickle cell disease:Feasibility,reliability and validity[J].Pediatric Blood & Cancer,2014,61(1):171-177. [10] Varni JW,Beaujean A,Limbers CA.Factorial invariance of pediatric patient self-reported fatigue across age and gender:A multigroup confirmatory factor analysis approach utilizing the PedsQL^TM Multidimensional Fatigue Scale[J].Quality of Life Research,2013,22(9):2581-2594.
[11] Kaleyias J,Manley P,Kothare SV.Sleep disorders in children with cancer[J].Semin Pediatr Neurol,2012,19(1):25-34.
[12] Hockenberry-Eaton M,Hinds PS,Alcoser P,et al.Fatigue in children and adolescents with cancer[J].Journal of pediatric Oncology Nursing,1998,15(3):172-182.
[13] Gordijn MS,van Litsenburg RR,Gemke RJ,et al.Sleep,fatigue,depression,and quality of life in survivors of childhood acute lymphoblastic leukemia[J].Pediatr Blood Cancer,2013,60(3):479-485.