Objective To investigate the difference of the maternal and neonatal complications between twins in vitro fertilization (IVF) and twins conceived naturally. Methods From January 2010 to December 2013, 110 cases twins IVF babies(IVF group), and 86 cases twins conceived naturally infants (conceived naturally group) were collected, and compared the general situation, delivery situation, the pregnancy complications of two groups mothers and the general situation, complications, treatment of neonatal were compared. Results 1) The mother's age of IVF group was older than conceived naturally group (P<0.001), the former's gestational age was much younger than the latter (P<0.001), and others had no statistical significance (P>0.05).2)In mother's pregnancy complications, this study found eight kinds of complications, thrombophilia and gestational hypertension of IVF group were higher than conceived naturally group (P<0.05), gestational diabetes mellitus(GDM) of conceived naturally group was higher than IVF group (P<0.05), the threatened premature labor and the premature rupture of membrane had no obvious differences in these two groups (P>0.05).3)The newborn birth weight of IVF group was less than conceived naturally group (P<0.05), and others had no statistical significance (P>0.05).4)In neonatal complications, this study found 20 kinds of complications.It found only premature infant brain injury of IVF group was higher than conceived naturally group (P<0.05), and other diseases had no difference(P>0.05). Conclusions The twins' mother of IVF group is older, smaller gestational age, and more likely to happen thrombophilia and high blood pressure during pregnancy, IVF baby has small born weight, and high incidence of premature infant brain injury;the twins' mother of conceived naturally has a greater incidence of gestational diabetes mellitus.The number of maternal and neonatal complications caused by different ways of twins pregnancy have no significant difference.
Key words
twins /
IVF baby /
conceived naturally /
newborn /
complications /
clinical analysis
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