Objective To understand functions of neonatal congenital hypothyroidism (CH),phenylketonuria (PKA),G6PD deficiency and hearing screening,and to find out their screen status. Method The analysis of neonatal disease screening results were deployed to accomplish statistical report of Yulin in 2013. Results 1)The number of CH screening was 110 650 cases,positive in 1 381 cases,the positive rate of screening was 1.25%,there were significant differences in districts (P<0.01);2)The number of PKU screening was 110 650 cases,the positive was in 387 cases,the positive rate of screening was 0.35%,there were significant differences in districts(P<0.01);3)The number of G6PD deficiency screening was 88 748 cases,positive was in 4 143 cases,the positive rate of screening was 4.67%,there were statistically significant differences in districts (P<0.01);4)The number of hearing screening was in 56 113 cases,positive was in 4 053 cases,the positive rate was 7.22%,and there were statistically significant differences in each district (P<0.01). Conclusion To carry out diseases screening of newborn comprehensively,can detect diseases of newborn,also provide valuable medical basis for early intervention of neonatal,this is an important way to improve quality of the population.