Objective To analysis the subjective living-quality and the social adaptive behavior in children with Tourette syndrome (TS) and to provide guidance for clinical treatment. Methods The subjective living-quality and the social adaptive behavior of 112 TS children (≥8 years old) were measured by means of Inventory of Subjective Life Quality (ISLQ),Children Behavior Checklist (CBCL) and Social of Adaptive Behavior (SAB) scales. Results The 7 aspect scores of ISLQ (in fact,7 aspects of them) in TS children were lower than those in control group (P＜0.01).The scores of behavior problems in TS children was higher than that in control group (P＜0.05).The ADQ in TS children was lower than that in control group (P＜0.05).Particularly the cognitive function and social /self direction were lower than those in control group(P＜0.001). Conclusions There are many problems in TS children' subjective living-quality and social adaptive behavior.Appropriate intervention should be given timely to promote the psycho-behavioral rehabilitation of TS children.