Objective To understand the breast feeding situation of Hui nationality infants in Xining and Xi'an. Methods There were 287 infants (Hui 168 and Han 119, aged 6~24 months) from Xining, 215 infants (Hui 114 and Han 101, aged 6~24 months) from Xi'an in this study, and people who feed the babies at the breast were included for analysis as well. Results 1)The rate of pure breast feeding in 4 months (58.54%) in Xining was higher than that (43.72%) in Xi'an (P<0.05), however, the rate of pure breast feeding in 6 months (19.51%) in Xining was lower than that (32.09%) in Xi'an (P<0.05);2)The rate of pure breast feeding of Hui nationality infants in 4 months (58.33%) in Xining was higher than that (39.47%) in Xi'an (P<0.05);3)The main reason for no pure breast feeding was milk secretion insufficiency (76.25%);4)The time of adding food supplement in Xining was (4.48±1.60) months, which was earlier than (5.67±1.59) months in Xi'an (P<0.05);5)A positive correlation was revealed between the rate of pure breast feeding and the culture level of people who feed the infants (P<0.05). Conclusions Strengthening the propaganda in the scientific feeding knowledge for people who feed the infants, is the key to improve the rate of breast feeding in western area.