: Objective To explore risk factors of small-for-gestational-age (SGA) births excluding mother's critical basal disease and obstetric risk factors. Methods A total of 550 SGA and 720 appropriate gestational age newborns were analyzed.Mother's stature, body weight, passive smoking and previous abortion or preterm history were collected and stepwise multivariable logistic regression model was constructed for the outcome. Results Risk factors to SGA were pregnant women with low pre-pregnancy body mass index (<18.5 kg/m2, OR=2.16, 95%CI:1.53~3.16), short stature (<155 cm, OR=2.46, 95%CI:1.78~3.48), low weight gain during pregnancy (<9 kg, OR=1.92, 95%CI:1.56~2.58) and passive smoking during pregnancy(OR=2.24, 95%CI:1.65~2.98).Pre-pregnancy BMI>24(OR=0.59, 95%CI:0.42~0.86)and weight gain during pregnancy >18 kg(OR=0.62, 95%CI:0.43~0.86)were protective factors of SGA. Conclusion Excluding known clinical risk factors, pre-pregnancy and pregnancy nutrition should be enhanced to add pregnant woman body weight, and protect them from passive smoking environment to reduce the prevalence of SGA.
Key words
small-for-gestational-age /
nutrition during pregnancy /
passive smoking /
risk factors
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] 吴洁, 毛萌.小于胎龄儿与胰岛素抵抗的研究进展[J].实用儿科临床杂志, 2006, 21(2):117-120.
[2] Hales CN, Barker DJ, Clark PM, et al.Fetal and infant growth and impaired glucose tolerance at age 64[J].BMJ, 1991, 303(6809):1019-1022.
[3] 张宝林, 冯泽康, 张丽辉, 等.中国15 城市的不同胎龄新生儿体格发育调查研究[J].中华儿科杂志, 1988, 26(4):206-209.
[4] 中国肥胖工作组数据汇总分析协作组.我国成年体重指数和腰围对相关疾病危险因素异常的预测价值:适宜体重指数和腰围切点的研究[J].中华流行病学, 2002, 23(1):5-10.
[5] 韩京秀, 甘德坤, 翟桂荣, 等.孕期不同阶段被动吸烟对足月产小于胎龄儿影响的病例-对照研究[J].卫生研究, 2006, 36(6):788-790.
[6] 王庆红, 杨于嘉, 魏克伦, 等.我国小于胎龄儿现状分析[J].中国实用儿科杂志, 2009, 24(3):177-179.
[7] Campbell J, Torres S, Ryan J, et al.Physical and nonphysical partner abuse and other risk factors for low birth weight among full term and preterm babies:a multiethnic case control study[J].American Journal of Epidemiology, 1999, 150(7):714-726.
[8] Lisbet S, Lundsberg, Bracken MB, et al.Low-to-moderate gestational alcohol use and intrauterine growth rretardation, low birthweight and preterm delivery[J].Ann Epidemiol, 1997, 7:498-508.
[9] Watanabe H, Inoue K, Doi M, et al.Risk factors for term small for gestational age infants in women with low pregnancy body mass index[J].J Obstet Gynaecol Res, 2010, 36(3):506-512.
[10] 卞义华, 马凤英.小于胎龄儿发生的危险因素及其防治策略[J].中国妇幼保健, 2013, 28 (16):2647-2649.
[11] Thompson JMD, Clark PM, Robinson E.Risk factors for small-for-gestational-age babies:the Auckland birthweight collaborative study[J].J Paediatr Child Health, 2001, 37:369-375.
[12] 甘德坤, 焦力, 朴文花, 等.非吸烟人群健康影响研究进展[J].环境与健康杂志, 2000, 17 (2):125-128.
[13] Papastefanou I, Souka AP, Pilalis A, et al.First trimester prediction of small- and large-for-gestation neonates by an integrated model incorporating ultrasound parameters, biochemical indices and maternal characteristics[J].Acta Obstet Gynecol Scand, 2012, 91(1):104-111.
PDF(395 KB)
