Analysis of multi-pregnancies results on congenital hypothyroidism neonatal screening and suggestion about recall-back mode.

JIANG Xiang; LI Bei; JIA Xue-fang; CHEN Qian-yu; LI Hui

doi:10.11852/zgetbjzz2014-22-07-32

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Chinese Journal of Child Health Care ›› 2014, Vol. 22 ›› Issue (7) : 766-767. DOI: 10.11852/zgetbjzz2014-22-07-32

Analysis of multi-pregnancies results on congenital hypothyroidism neonatal screening and suggestion about recall-back mode.

JIANG Xiang, LI Bei, JIA Xue-fang, CHEN Qian-yu, LI Hui

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Abstract

Objective To study the relationship of congenital hypothyroidism screening results with multi-pregnancies in newborn infants. Methods Detection of thyroid stimulating hormone (TSH) concentration from blood specimens dried on fliter paper by Fluorescence Enzyme Immunoassay (FEIA).The neonates were divided into two groups according to multi-pregnancies, and the correlation was analysed between prevalence of CH and different pregnancies. Results A total of 424 472 infants were screened, and 194 cases were identified with CH.The prevalence rate was 1/2 188.The prevalence of singletons, multi-pregnancies were 1/2 237, 1/652 respectively.The prevalence of CH was significantly different between singletons groups and multi-pregnancy groups. Conclusions The prevalence of CH is associated with multi-pregnancies.In case of missed diagonosis of CH, it is strongly recommendable to recall them back if one of each multi-pregnancies results was positive.

Key words

congenital hypothyroidism / thyroid stimulating hormone / multi-pregnancies / twins / neonatal screening

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JIANG Xiang, LI Bei, JIA Xue-fang, CHEN Qian-yu, LI Hui. Analysis of multi-pregnancies results on congenital hypothyroidism neonatal screening and suggestion about recall-back mode.[J]. Chinese Journal of Child Health Care. 2014, 22(7): 766-767 https://doi.org/10.11852/zgetbjzz2014-22-07-32

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