Clinical analysis on the levels of IL-6 and TNF-α in blood plasma of neonates with intracranial haemorrhage.

LIU Yan-hong; ZHAO Xian-feng; JIA Mei-yun; YAN An-ping

doi:10.11852/zgetbjzz2014-22-07-21

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Chinese Journal of Child Health Care ›› 2014, Vol. 22 ›› Issue (7) : 733-734. DOI: 10.11852/zgetbjzz2014-22-07-21

Clinical analysis on the levels of IL-6 and TNF-α in blood plasma of neonates with intracranial haemorrhage.

LIU Yan-hong¹, ZHAO Xian-feng², JIA Mei-yun¹, YAN An-ping¹

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Abstract

Objective To explore the changes and clinical significance of serum levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in newborns with intracranial hemorrhage. Method The levels of IL-6 and TNF-α blood plasma in 50 neonates with intracranial haemorrhage (case group) and 26 healthy neonates (control group) were detected by ELISA. Results The levels of IL-6 and TNF-α in case group were significantly higher than those in control group (P<0.05);There were significant differences in levels of IL-6 and TNF-α between different amounts of bleeding group (P<0.05). Conclusions Serum levels of IL-6 and TNF-α creases obviously in newborns with intracranial hemorrhage, suggesting that they might be used as reference index in assessing pathogenetic condition and appraising prognosis.

Key words

intracranial haemorrhage / interleukin-6 / tumor necrosis factor-α / neonates

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LIU Yan-hong, ZHAO Xian-feng, JIA Mei-yun, YAN An-ping. Clinical analysis on the levels of IL-6 and TNF-α in blood plasma of neonates with intracranial haemorrhage.[J]. Chinese Journal of Child Health Care. 2014, 22(7): 733-734 https://doi.org/10.11852/zgetbjzz2014-22-07-21

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