Objective To assess the value of fractional exhaled nitric oxide (FeNO) monitor in the control of children with asthma. Methods A total of 50 children with light, moderate and severe asthma from department of allergy were selected into the experimental group.FeNO concentrations, pulmonary function test, the score of the day night time asthma symptom were detected and analyzed before and after treatment of 3 months and 6 months .At the same period, 50 cases of healthy control group were detected FeNO. Results 1)Compared with no treatment, FeNO value decreased significantly after 3 months treatment, the difference was statistically significant (P<0.000 1), but there was no statistically significant difference between the 3 months and 6 months treatment (P>0.05) in the experimental group.2)FeNO concentrations and the score of symptom in the day night time asthma were all decreased significantly for 3 months and 6 months treatment in the experimental group.The FEV1% , the FVC, the PEF value of lung function were all increased significantly for 3 months and 6 months treatment in the experimental group(P＜0.05).3)The FeNO value before and after treatment in the experimental group were significantly higher than that in the control group (P<0.000 1). Conclusion FeNO concentrations can evaluate airway inflammation in children with asthma as a good indicator.
Key words
asthma /
fractional exhaled nitric oxide /
children
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