热性惊厥儿童的智力水平和智力结构分析
- 石冰心1,2,赵亚茹2,谭迎花2,姜淑萍2
作者信息
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Intelligence level and structure in children with febrile seizures
- SHI Bing-xin1,2,ZHAO Ya-ru2,TAN Ying-hua2,JIANG Shu-ping2
Author information
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文章历史
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摘要
目的 分析热性惊厥(febrile seizures,FS)儿童学龄期的智力水平和智力结构状况。方法 采用中国韦氏儿童智力量表(China Wechsler Intelligence Scale of Children,C-WISC)对30例有单纯型热性惊厥(simple febrile seizures,SFS)史、30例有复杂型热性惊厥(complex febrile seizures,CFS)史和34例无热性惊厥史的正常健康儿童进行智商测定,并对其智力结构进行分析。结果 SFS组、CFS组和对照组的总智商(full intelligence quotient,FIQ)、言语智商(verbal IQ,VIQ)、操作智商(performance IQ,PIQ),差异均无统计学意义(P>0.05)。CFS组与对照组比较,编码及分类差异有统计学意义(F=3.169,2.967,P均<0.05),两组智商中的记忆/注意因子(M/C)差异有统计学意义(F=3.082,P<0.05)。SFS组、CFS组分别与对照组比较,VIQ与FIQ平衡性测试(差值)结果比较差异有统计学意义(χ2=4.099,6.461,P<0.05)。 结论 FS儿童的总体智力水平正常,但智力结构不平衡,CFS儿童记忆/注意因子(M/C)存在一定缺陷,提示CFS儿童可能存在与记忆、注意相关的脑功能损害。
Abstract
Objective To explore the characteristics of the intelligence level and structure in school-aged children with a history of febrile seizures (FS). Methods Thirty children with a history of simple febrile seizures (SFS),30 children with a history of complex febrile seizures (CFS) and 34 children without a history of FS were assessed using China Wechsler Intelligence Scale of Children(C-WISC).The scores among groups were compared.Results The full intelligence quotient (FIQ),verbal IQ (VIQ) and performance IQ (PIQ) in the SFS and CFS group were in normal ranges and did not different from the normal group.There were significant differences in the scores for coding,similarities and M /C factor between the CFS group and normal group (F=3.169,2.967,3.082,P<0.05).There was significantly different in balancing tests of three groups (χ2=4.099,6.461,P<0.05). 【Conclusions】 It is normal in the total intelligence level of FS children,but there are imbalances in the intelligence structure.The M /C factor of CFS children have some defects and CFS children might be brain dysfunction associated with memory and attention.
关键词
Key words
febrile seizures / intelligence structure / school-aged children
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参考文献
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[2] 吴启华.小儿神经系统疾病[M].2版.北京:人民卫生出版社,2002:424-434.
[3] 常杏芝,秦炯,游石琼,等.反复热性惊厥对大鼠学习记忆影响及其机制[J].实用儿科临床杂志,2003,18(3):169-171.
[4] Sadleir LG,Scheffer IE.Febrile seizures[J].BMJ,2007,334:307-311.
[5] Dube C,Richichi C,Bender RA,et al.Temporal lobe epilepsy after experimental prolonged febrile seizures:Prospective analysis[J].Brain,2006,129(4):911-922.
[6] 郑乃智,于谭芳,解学孔.热性惊厥的研究进展[J].国外医学神经病学神经外科学分册,2002,29(1):71-73.
[7] 曹丽娟,郑小琳,赵曼华,等.儿保门诊应用韦氏儿童智力量表的效果[J].中国妇幼保健,2006,21(16):2246-2248.
[8] 吴小慧,麦坚凝,杨思渊.热性惊厥影响患儿行为的研究[J].中国实用儿科杂志,2009,24(7):548-551.
[9] Natsume J,Bernasconi N,Miyauchi M,et al.Hippocampal volumes and diffusion-weighted image findings in children with prolongedfebrile seizures[J].Acta Neurol Scand,2007,115(4):25-28.
[10] 石冰心,赵亚茹,姜淑萍.热性惊厥对儿童持续性注意力影响的研究[J].中国儿童保健杂志,2011,19(5):460-462.
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