注意缺陷多动障碍儿童工作记忆的研究进展
- 陈礼彬 综述, 陈燕惠 审校
作者信息
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文章历史
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摘要
研究表明注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)患儿常伴有认知功能障碍,其中,工作记忆(Working Memory,WM)是ADHD患儿的核心缺陷,而工作记忆在高水平的认知活动当中起重要作用。关于ADHD患儿工作记忆的研究不断深入,但研究结果却存在争议,下面从神经心理学、神经分子学与基因组学、神经解剖学与神经影像学以及神经电生理学等方面,就ADHD患儿工作记忆的研究进展方面作一综述。
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参考文献
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[16] Aguiar A,Eubig PA,Schantz SL.Attention deficit/hyperactivity disorder:a focused overview for children's environmental health researchers[J].Environ Health Perspect,2010,118(12):1646-1653.
[17] Cortese S,Kelly C,Chabernaud C,et al.Toward systems neuroscience of ADHD:a meta-analysis of 55 fMRI studies[J].Am J Psychiatry,2012,169(10):1038-1055.
[18] Szobot CM,Roman T,Hutz MH.Molecular imaging genetics of methylphenidate response in ADHD and substance use comorbidity[J].Synapse,2011,65(2):154-159.
[19] Shen LH,Liao MH,Tseng YC.Recent advances in imaging of dopaminergic neurons for evaluation of neuropsychiatric disorders[J].J Biomed Biotechnol,2012,2012:259349.
[20] 杜亚松,龚云,刘漪,等.哌甲酯治疗前后注意缺陷多动障碍患儿视觉P300和非匹配负波的变化[J].实用儿科临床杂志,2011,26(19):1520-1522,1536.
[21] Myatchin I,Lemiere J,Danckaerts M,et al.Within-subject variability during spatial working memory in children with ADHD:an event-related potentials study[J].Eur Child Adolesc Psychiatry,2012,21(4):199-210.
[22] 陈晶,陈燕惠.儿童注意缺陷多动障碍的脑电活动研究进展[J].临床神经电生理学杂志,2008,17(5):311-314.
[23] Snyder SM,Hall JR.A meta-analysis of quantitative EEG power associated with attention-deficit hyperactivity disorder[J].J Clin Neurophysiol,2006,23(5):440-455.
[2] Frodl T,Skokauskas N.Meta-analysis of structural MRI studies in children and adults with attention deficit hyperactivity disorder indicates treatment effects[J].Acta Psychiatr Scand,2012,125(2):114-126.
[3] Baddeley AD.Working memory[M].NewYork:Oxford University Press,1986:33-34.
[4] Baddeley A.Working memory:looking back and looking forward[J].Nat Rev Neurosci,2003,4(10):829-839.
[5] Edin F,Klingberg T,Johansson P,et al.Mechanism for top-down control of working memory capacity[J].Proc Natl Acad Sci USA,2009,106(16):6802-6807.
[6] 李茜茜,郭兰婷,黄雪竹,等.注意缺陷多动障碍混合型和注意缺陷型的神经心理特征分析[J].中华儿科杂志,2008,46(1):64-68.
[7] Rhodes SM,Park J,Seth S,et al.A comprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder[J].J Child Psychol Psychiatry,2012,53(2):128-137.
[8] Gibson BS,Gondoli DM,Flies AC,et al.Application of the dual-component model of working memory to ADHD[J].Child Neuropsychol,2010,16(1):60-79.
[9] Dovis S,Van der Oord S,Wiers RW,et al.Can motivation normalize working memory and task persistence in children with attention-deficit/hyperactivity disorder? The effects of money and computer-gaming[J].J Abnorm Child Psychol,2012,40(5):669-681. [10] Wallace TL,Ballard TM,Pouzet B,et al.Drug targets for cognitive enhancement in neuropsychiatric disorders[J].Pharmacol Biochem Behav,2011,99(2):130-145.
[11] Diamond A.Biological and social influences on cognitive control processes dependent on prefrontal cortex[J].Prog Brain Res,2011,189:319-339.
[12] Kieling C,Genro JP,Hutz MH,et al.A current update on ADHD pharmacogenomics[J].Pharmacogenomics,2010,11(3):407-419.
[13] Linssen AM,Vuurman EF,Sambeth A,et al.Methylphenidate produces selective enhancement of declarative memory consolidation in healthy volunteers[J].Psychopharmacology (Berl),2012,221(4):611-619.
[14] Brown AB,Biederman J,Valera E,et al.Relationship of DAT1 and adult ADHD to task-positive and task-negative working memory networks[J].Psychiatry Res,2011,193(1):7-16.
[15] Archer T,Kostrzewa RM.Physical exercise alleviates ADHD symptoms:regional deficits and development trajectory[J].Neurotox Res,2012,21(2):195-209.
[16] Aguiar A,Eubig PA,Schantz SL.Attention deficit/hyperactivity disorder:a focused overview for children's environmental health researchers[J].Environ Health Perspect,2010,118(12):1646-1653.
[17] Cortese S,Kelly C,Chabernaud C,et al.Toward systems neuroscience of ADHD:a meta-analysis of 55 fMRI studies[J].Am J Psychiatry,2012,169(10):1038-1055.
[18] Szobot CM,Roman T,Hutz MH.Molecular imaging genetics of methylphenidate response in ADHD and substance use comorbidity[J].Synapse,2011,65(2):154-159.
[19] Shen LH,Liao MH,Tseng YC.Recent advances in imaging of dopaminergic neurons for evaluation of neuropsychiatric disorders[J].J Biomed Biotechnol,2012,2012:259349.
[20] 杜亚松,龚云,刘漪,等.哌甲酯治疗前后注意缺陷多动障碍患儿视觉P300和非匹配负波的变化[J].实用儿科临床杂志,2011,26(19):1520-1522,1536.
[21] Myatchin I,Lemiere J,Danckaerts M,et al.Within-subject variability during spatial working memory in children with ADHD:an event-related potentials study[J].Eur Child Adolesc Psychiatry,2012,21(4):199-210.
[22] 陈晶,陈燕惠.儿童注意缺陷多动障碍的脑电活动研究进展[J].临床神经电生理学杂志,2008,17(5):311-314.
[23] Snyder SM,Hall JR.A meta-analysis of quantitative EEG power associated with attention-deficit hyperactivity disorder[J].J Clin Neurophysiol,2006,23(5):440-455.
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