目的 分析新生儿高胆红素血症的病因,为临床诊疗提供参考。 方法 对2009年1月-2012年2月本院收住院治疗的193例新生儿高胆红素血症资料进行进行回顾性分析。 结果 193例黄疸的发生因素依次为:围生期因素(28.0%),母乳性黄疸(16.6%),新生儿溶血病(15.0%),新生儿感染因素(14.5%),母孕期胎儿肝脏损伤(11.4%),先天因素以及其它因素等(14.5%)。治疗主要有蓝光照射,输用白蛋白;祛除病因如换血治疗,抗感染,母乳性黄疸暂停母乳等以及各种辅助治疗。193例新生儿高胆红素血症中,治愈和好转184例。 结论 导致新生儿高胆红素血症病因多样,围生期因素、母乳性黄疸、新生儿溶血病是最常见因素,应引起临床医生重视。

Objective To study the etiology of neonatal hyperbilirubinemia. Method A total of 193 cases of neonatal hyperbilirubinemia were analyzed in the Rizhao Maternal and Child Health Hospital from January 2009 to February 2012 retrospectively. Results The etiological factors of neonatal hyperbilirubinemia of 193 cases were:perinatal factors (28%),breast milk jaundice (16.6%),hemolytic disease of the newborn (15%),neonatal infection factors (14.5%),maternal fetal liver injury (11.4%),congenital factors and other factors (14.5%).The main therapy methods were the blue light,albumin injection;dispel pathogeny including exchange transfusion therapy,anti-infection,suspend breast-feeding when breast milk jaundice,as well as various adjuvant treatment.In 193 cases of neonatal hyperbilirubinemia,in 184 cases were cured or improved diversified. Conclusion A variety of causes leading to neonatal hyperbilirubinemia are diversified.Perinatal factors,breast milk jaundice,hemolytic disease of the newborn are most common factors.