摘要
儿童青少年代谢综合征发病率逐年增加,并与成年期健康密切相关。肥胖,尤其是腹型肥胖是代谢综合征成分中最重要的危险因素,而早期营养程序化是儿童肥胖发生和发展的重要机制。加强营养程序化窗口期的预防和肥胖儿童生活方式管理的研究和临床应用,是儿科医生未来预防和控制儿童青少年代谢综合征发展努力的方向。
关键词
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参考文献
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[13] 王斐,陈梦莹,陈海燕,等.健康教育对肥胖儿童认知、膳食结构及生活方式的影响[J].中国儿童保健杂志 2012,20(11):966-970.
[14] O'Connor TM,Yang SJ,Nicklas TA.Beverage intake among preschool children and its effect on weight status[J].Pediatrics,2006,118(4):1010-1018.
[15] Poetaa LS,Duarte MD,Caramellic B,et al.Effects of physical exercises and nutritional guidance on the cardiovascular risk profile of obese children[J].Rev Assoc Med Bras,2013,59(1):56-63.
[16] Osei-Assibey G,Dick S,Macdiarmid J,et al.The in fluence of the food environment on overweight and obesity in young children:a systematic review[J].BMJ Open,2012,2(6):1-12.
[2] Dorner G.Perinatal hormone levels and brain organization.[M]//Stumpf WE,Grant LD,eds.Anatomical neuroendocrinology.Basel,Switzerland:Karger,1975:245-252.
[3] Barker DJ.Fetal origins of coronary heart disease[J].BMJ,1995,311(6998):171-174.
[4] Lucas A.Programming by early nutrition:an experimental approachl[J].Nutr,1998,128(2S):401-406.
[5] Berthold K,Brigitte B,Demmelmair H,et al.The Early Nutrition Programming Project (EARNEST):5y of successful multidisciplinary collaborative research[J].Am J Clin Nutr,2011,94(S):1749-1753.
[6] Hou M,Ji CL,Wang J,et al.The effects of dietary fatty acid composition in the post-sucking period on metabolic alterations in adulthood: can u3 polyunsaturated fatty acids prevent adverse programming outcomes？[J].Journal of Endocrinology,2012;215(1):119-127.
[7] Singhal A,Kennedy K,Lanigan J,et al.Nutrition in infancy and long-term risk of obesity: evidence from 2 randomized controlled trials1-3[J].Am J Clin Nutr,2010,92 (5):1133-1144.
[8] Zhu LJ,Hou M,Sun B,et al.Testosterone stimulates adipose tissue 11{beta}-dehydrogenase type 1 expression in a depot-specific manner in children[J].JCEM,2010,95(6):3300-3308.
[9] Bibbins-Domingo K,Coxson P,Pletcher MJ,et al.Adolescent overweight and future adult coronary heart disease[J].N Engl J Med,2007,357(23):2371-2379.
[10] Koletzko B,Symonds ME,Olsen SF.Programming research.Where are we and where do we go from here?[J].Am J Clin Nutr,2011,94(S):2036-2043.
[11] Paul IM,Savage JS,Anzman SL,et al.Preventing obesity during infancy:a pilot study[J].Obesity,2011,19(2):353-361.
[12] 史晓燕,陈梦莹,王斐,等.单餐大份量进食是儿童单纯性肥胖的饮食危险因素[J].营养学报,2011,33(2):138-142.
[13] 王斐,陈梦莹,陈海燕,等.健康教育对肥胖儿童认知、膳食结构及生活方式的影响[J].中国儿童保健杂志 2012,20(11):966-970.
[14] O'Connor TM,Yang SJ,Nicklas TA.Beverage intake among preschool children and its effect on weight status[J].Pediatrics,2006,118(4):1010-1018.
[15] Poetaa LS,Duarte MD,Caramellic B,et al.Effects of physical exercises and nutritional guidance on the cardiovascular risk profile of obese children[J].Rev Assoc Med Bras,2013,59(1):56-63.
[16] Osei-Assibey G,Dick S,Macdiarmid J,et al.The in fluence of the food environment on overweight and obesity in young children:a systematic review[J].BMJ Open,2012,2(6):1-12.
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