目的 定量评估陕西地区正常儿童双侧颈部动脉内中膜厚度及管壁弹性各项参数的大致范围,为动脉粥样硬化早期诊断和儿童期干预提供正常参考数据。方法 对150例正常儿童志愿者应用超声射频信号血管内中膜分析技术QIMT及超声射频信号动脉僵硬度分析技术QAS获取双侧颈动脉的内中膜厚度(IMT) 、顺应性指标(膨胀系数DC、顺应系数CC)及僵硬度指标(反射波增强指数AIX、α系数、β系数、脉搏波传导速度PWV),确定各项参数儿童期的大致范围。结果 1)陕西地区7~15岁正常儿童IMT(441.483±85.126)μm,DC(0.077±0.030)mm²/kPa,CC(2.290±0.952)mm²/kPa,AIX(-2.804±2.449),α系数(1.453±0.519),β系数(3.002±1.050),PWV(3.650±0.558) m/s;2)颈动脉左右侧之间、不同性别间颈动脉各项参数差异无统计学意义(P值均>0.05)。 结论 应用射频超声技术可准确提供陕西地区正常儿童期颈部动脉IMT厚度及血管弹性总体参数,为儿童干预预防动脉硬化提供科学依据。

Objective To quantitative evaluat the normal children carotid artery intima-media thickness(IMT) and wall elastic various parameters of the salary range,and provide normal reference data for atherosclerosis early diagnosis and childhood intervention in Shaanxi. Methods The quality intima-media thickness (QIMT)and quality arterial stiffness(QAS)of ultrasound radio frequency(RF)technology were applied for 150 normal children volunteer to obtain bilateral carotid intima-media thickness IMT,compliance index (distend compliance DC,conform compliance CC) and stiffness index (augmentation index AIX,a coefficient,βcoefficient,pulse wave velocity PWV),parameters childhood range. Results 1)Normal children aged 7~15 in Shaanxi had IMT(441.483±85.126)μm,DC(0.077±0.030)mm²/kPa,CC(2.290±0.952)mm²/kPa,AIX(-2.804±2.449),α(1.453±0.519),β(3.002±1.050),PWV(3.650±0.558) m/s.2)Carotid artery between the right and left sides,between the different gender carotid parameters showed no significant differences. Conclusion Application of radio frequency ultrasound technology can accurately provide normal childhood common carotid artery intima-media thickness IMT,vascular elastic parameter,and scientific basis for intervention in the prevention of arteriosclerosis in Shaanxi area.