孤独症儿童的脑干听觉诱发电位检测结果临床分析
- 颜华,张惠佳,郭春光,周平秋,何金华,苏珍辉,阳伟红,王益梅
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Analysis of the brainstem auditory evoked potential in the children with autism.
- YAN Hua,ZHANG Hui-jia,GUO Chun-guang,ZHOU Ping-qiu,HE Jin-hua,SU Zhen-hui,YANG Wei-hong,WANG Yi-mei.
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摘要
目的 探讨孤独症患儿脑干听觉诱发电位(brainstem auditory evoked potential,BAEP)的临床特征,为临床工作指导提供参考依据。方法 对78例孤独症患儿的BAEP检测结果进行分析。结果 78例患儿中,BAEP正常33例(42.3%),异常45例(57.7%),主要表现为波幅改变、波潜伏期、 峰间期延长、波形分化不良或听阈值增高。 结论 孤独症患儿听力基本正常,但存在BAEP异常,提示脑干听觉传导通路异常可能是造成其认知与语言发育障碍的原因之一。
Abstract
Objective To investigate the characteristics of brainstem auditory evoked potential (BAEP) in children with autism. Method The data of BAEP in the children with autism was analysed. Results BAEP of 33 children among 78 cases were normal,the rest were abnormal,mainly including changed wave amplitude,the prolonged wave latency,long interpeak latency,poor wave form differentiation and increased hearing threshold level. Conclusion Acouesthesia of autistic children is almost normal,but the brainstem transmission time of BAEP is prolonged,which indicate that auditory brainstem dysfunction may lead to the dysplasia of cognitive and language development.
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参考文献
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[3] 张艳,宿英英.脑干听觉诱发电位分级标准评价脑功能损伤的研究[J].中国急救医学,2003,23(9):623-624.
[4] Ryson SE,Bradley EA,Thompson A,et al.Prevalence of autism among adolescents with intellectual disabilities[J].Can J Psychiatry,2008,53(7):449-459.
[5] 谭迎花,郗春艳.儿童孤独症听觉反应异常的研究进展[J].国际儿科学杂志,2011,38(1):50-52.
[6] Robel L.Evolution of the concept of autism[J].Rev Part,2010,60(3):376-378.
[7] 楼翡璎,陈兴时,张明岛,等.孤独症儿童感觉门控的临床随访研究[J].神经病学与神经康复学杂志,2011,8(1):22-24.
[8] 张楠,李玉茹.自闭症患儿听觉诱发反应检测分析[J].听力学及言语疾病杂志,2008,16(2):129-131.
[9] Kwon S,Kim J,Choe BH,et al.Electrophysiologie assessment of crat auditory processing by auditory brainstem responses in child with autism spectrum disorders[J].J Korean Med Sci,2007,22(4):656-659.
[10] Tas A,Yagiz R,Tas M,et al.Evaluation of hearing In children with autism by using TEOAE and ABR[J].Autism,2007,11(1):73-79.
[11] Waigenbaum L.Advances in the early detection of autism[J].Curr Opin Neurol,2010,23(2):97-102.
[12] 吴荣琴,张少靓,张广歧,等.脑干听觉反应在青少年精神分裂症和孤独症中的应用[J].现代电生理学杂志,2010,17(2):74-76.
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