【目的】 研究影响肥胖学龄期儿童的血压升高的家庭相关危险因素,为儿童肥胖以及相关高血压的预防和治疗提供依据。 【方法】 采用Cox比例风险模型对124例肥胖儿童进行高血压的家庭相关因素分析。 【结果】 多因素Cox回归分析结果显示,母亲肥胖、父亲肥胖、家族高血压人数和出生体重在肥胖儿童发生高血压的相对危险度分别为2.117、1.969、1.828和1.777,P值均<0.05。 【结论】 父母肥胖、有高血压家族史以及出生体重巨大的肥胖儿童是早期发生高血压的高危人群。
Abstract
【Objective】 To study the related family factors on hypertension in school-age children with simple obesity. 【Method】 The correlative analysis for hypertension in obesity children and the risk factors of their family were done by COX multiple variable analysis. 【Result】 Cox regression analysis showed the relative risk of mother obese,father obese,family history of hypertension and birth weight were 2.117,1.969,1.828 and 1.777 respectively(All P<0.05). 【Conclusion】 The obese children with obese parents,family history of hypertension or large birth weight are at high risk of early onset of hypertension.
关键词
肥胖 /
儿童 /
高血压 /
家庭相关因素
Key words
obesity /
children /
hypertension /
family-related factors
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Heber D.An integrative view of obesity[J].Am J Clin Nutr,2010,91(S):280-283.
[2] Manu Raj.Obesity and cardiovascular risk in children and adolescents[J].Indian J Endocrinol Metab,2012,16(1):13-19.
[3] 王惠,钟历勇.肥胖相关高血压的研究进展[J].东南大学学报:医学版,2003,22(3) :207-210.
[4] 中国肥胖问题工作组.中国学龄儿童青少年超重、肥胖筛查体重指数值分类标准[J].中华流行病学杂志,2004,25(2):97-102.
[5] 米杰,王天有,孟玲慧,等.中国儿童青少年血压参照标准的研究制定[J].中国循证儿科杂志,2010,5(1):4-6.
[6] 朱敏敏.高血压家族史儿童血压水平的研究[J].心血管康复医学杂志,2009,18(5):425-427.
[7] 王念蓉,王继林.重庆城区3~18岁儿童肥胖和血压的关系[J].中国儿童保健杂志,2008,16(6):670-673.
[8] Owen CG,Whincup PH,Orfei L,et al.Is body mass index before middle age related to coronary heart disease risk in later life? Evidence from observational studies[J].Int J Obes (Lond),2009,33:866-877.
[9] I'Allemand D,Wiegand S,Reinehr T,et al.Cardiovascular risk in 26,008 European overweight children as established by a multicenter database[J].Obesity (Silver Spring),2008,16:1672-1679.
[10] Lobstein T,Baur L,Uaul R.Obesity in children and young people:A crisis in public health[J].Obes Rev,2004,5(S):4-8.
[11] 张晓铭,张美仙,侯冬青.出生体重对儿童期和成年期高血压影响的队列研究[J].中国循证儿科杂志,2011,6(3):199-204.
[12] Flynn JT,Alderman MH.Characteristics of children with primary hypertension seen at a referral center[J].Pediatr Nephrol,2005,20(7):961-966.
[13] 赵仁兵,王予川,刘君实.家族遗传对少年儿童高血压患病率及血压水平的影响[J].贵州医药,2008,32(11):1026-1027.
[14] Tian JY,Cheng Q,Song XM,et al.Birth weight and risk of type 2 diabetes,abdominal obesity and hypertension among Chinese adults[J].Eur J Endocrino,2006,155(4):601-607.
PDF(446 KB)
