【目的】 本研究对注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)患儿给予视频长程脑电图监测,探讨视频长程脑电图对于注意缺陷多动障碍的临床意义。 【方法】 从小儿神经专科门诊中收集ADHD病例以及正常对照组,给予所有入组对象视频长程脑电图描记。 【结果】 ADHD组儿童脑电图异常率较正常对照组高,表现为θ波、δ波增多,异常放电增多。分6~7、7~8、9~14岁三个年龄段比较ADHD组与正常对照组清醒期脑电图α节律波幅以及频率,ADHD各年龄组α节律平均波幅、平均频率低于正常对照组,差异均有统计学意义(P<0.05)。通过视频长程脑电图检查,从脑电图异常率、α节律平均波幅、平均频率等神经电生理指标比较反映出ADHD组脑功能存在异常,神经元兴奋性较正常降低。 【结论】 视频长程脑电图检查可以真实反映ADHD患者脑功能,对临床诊疗ADHD有一定帮助。
Abstract
【Objective】 To analyse the clinical significance of video long-range electroencephalogram(EEG)in children suffering from attention deficit hyperactivitydisorder(ADHD),so as to discuss the importance of the video long-range electroencephalogram for ADHD. 【Methods】 The patients of ADHD and the normal group both were from outpatient of pediatric neurology,and the video long-range electroencephalogram was monitored in all of them. 【Results】 The video long-range electroencephalogram abnormal rate was higher in ADHD than normal,it showed that there were much more wave θ、δ and abnormal electro-discharge.Divided the patients of ADHD into three groups by age as following 6~7 years,7~8 years,9~14 years,and each group was compared with the normal group in amplitude and frequency of wave α in awake EEG.And there was significant difference in average amplitude and frequency of wave between the three ADHD group and the normal group(P<0.05),the ADHD was inferior to the normal.Nerve electricity physiological indexes indicated that the neurons excitability of ADHD was decline. 【Conclusions】 The video long-range electroencephalogram is helpful to the diagnose and treatment of ADHD,it plays a very important role that should not be neglect.
关键词
脑电图 /
视频长程监测 /
注意缺陷多动障碍
Key words
attention deficit hyperactivity disorders /
electroencephalogram /
video of long-range monitoring
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参考文献
[1] 王玉凤.关注注意缺陷多动障碍研究进展[J].北京大学学报,2007,39(3):217-219.
[2] Barkley RA.Attention-deficit hyperactivity disorder:a handbook for diagnosis and treatment[M].1998,Guildford Publications,New York:American Psychiatric Association,DSM-IV TR,2000.
[3] American Psychiatric Association.Diagnostic and statistical manual for mental disorders[M].4th ed.Washington,DC:American Psychiatric Association,1994:78-85.
[4] 刘晓燕.临床脑电图学[M].北京:人民卫生出版社,2006:214-215.
[5] 郭蕴岚,郭蕴琦,王家勤,等.哌甲酯对注意缺陷多动障碍患儿脑电图的影响[J].实用儿科临床杂志,2010,25(21):1675-1676.
[6] 孙黎,王玉凤,何华,等.注意缺陷多动障碍儿童服用单剂量哌甲酯后脑电α波的变化[J].中国心理卫生杂志,2009,23(8):584-589.
[7] 尚煜,李琦,闻承生,等.ADHD儿童脑电特征及与脑功能的关系[J].中国心理卫生杂志,2006,20(8):504-505.
[8] Clarke AR,Barry RJ,McCathy R,et al.EEG defined subtypes of children w ith attention deficit hyperactivity disorder[J].Clin Neurophysiol,2001,112(11):2098-2105.
[9] Clarke AR,Barry RJ,McCathy R,et al.EEG evidence fora new conceptualization of attention deficit hyperativity disorder[J].Clin Neurophysiol,2002,113(7):1036-1044.
[10] Clarke AR,Barry RJ,McCarthy R,et al.Coherence inchildren with attention deficit hyperactivity disorder andexcess beta activity in their EEG[J].Clin Neurophysiol,2007,118(7):1472-1479.
基金
2010福建省卫生厅青年科研项目(2010-2-22)