【目的】 探讨眼底检查对高危儿颅内出血(intracranial hemorrhage,ICH)的预测价值。 【方法】 回顾性分析本院在矫正胎龄45周内已行头颅CT/MRI及眼底检查的423例高危儿病例。 【结果】 颅内出血122例、眼底出血202例,眼底出血高危儿202例中头颅CT/MRI证实有颅内出血109人 (53.96%),无眼底出血高危儿中颅内出血13人(3.0%),经比较差异具有统计学意义(P<0.01)。有颅内出血高危儿的眼底出血程度与无颅内出血高危儿的眼底出血程度比较,差异有统计学意义(P<0.01)。颅内出血与眼底出血两者之间密切相关(R=62.02,P=0.000)。 【结论】 高危儿行眼底检查有助于预测其颅内出血的发生。
Abstract
【Objective】 To investigate the value of fundus examination in evaluating intracranial hemorrhage(ICH) in high risk infants. 【Method】 423 cases of high-risk infants,taken head CT/MRI and fundus examination before 45 weeks corrected gestational age in our hospital,were retrospective analyzed. 【Results】 122 cases of intracranial hemorrhage,202 cases of retinal hemorrhage,109 cases(53.96%) of ICH among the cases with retinal hemorrhage (RH) and 13 cases (3.0%) of ICH among the cases without RH were compared.The difference of ICH incidence had statistical significance(P<0.01).The difference of the degree of RH with and without ICH in high risk infants had statistical significance(P<0.01).ICH and RH were closely related(R=62.02,P=0.000). 【Conclusion】 Fundus examination could be predictive of ICH in high risk infants.
关键词
高危 /
围产儿 /
新生儿 /
颅内出血 /
眼底出血
Key words
high-risk /
perinatal infant /
newborn infant /
intracranial hemorrhage /
retinal hemorrhage
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 邵肖梅,叶鸿瑁,丘小汕.实用新生儿学[M].4版.北京:人民卫生出版社,2011:47-50.
[2] Looney CB,Smith JK,Merck LH,et al.Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors[J].Radiology,2007,242(2):535-541.
[3] Squier W,Mack J.The neuropathology of infant subdural hemorrhage[J].Forensic Sci Int,2009,187(1-3):6-13.
[4] Sirsi D,Nadiminti L,Packard MA,et al.Apneic seizures:a sign of temporal lobe hemorrhage in full-term neonates[J].Pediatr Neourl,2007,37(5):366-370.
[5] 刘莹,孙建梅,孙玉梅.新生儿ICH误诊情况分析及早期干预[J].中国妇幼保健杂志,2005,20(6):1027-1028.
[6] 刘敬,架继雯,王琪,等.早产儿脑室周围脑室内出血发生率调查及高危因素分析[J].中华儿科杂志,2005,43(3):216-218.
[7] Lavrijsen SW,Uiterwaal CS,Stigter RH,et al.Severe umbilical cord acidemia and neurological outcome in preterm and full-term neonates[J].Biol Neonate,2005,88(1):27-34.
[8] Dammann O,Leviton A.Perinatal brain damage causation[J].Dev Neurosci,2007,29(4-5):280-288.
[9] 李素芬,李艳芝,崔模,等.新生儿ICH合并RH63例临床分析[J].中华眼底病杂志,1994,10(1):30-31.
PDF(427 KB)
