【目的】 分析不同病情佝偻病(different rickets,DR)患儿血清中钙、磷、锌及骨碱性磷酸酶的水平。 【方法】 选择广州市地区DR患儿60例,并按不同病情分轻度、中、重度组,同时选择60例同期体检健康儿童一同进行血清钙、磷、锌及骨碱性磷酸酶的双盲检测。 【结果】 中、重度DR 组的血清钙、磷和锌水平均明显低于对照组,轻度DR组与对照组差异无统计学意义;DR组骨碱性磷酸酶均明显高于对照组(P均<0.05)。在DR组内,中、重度DR 组的外周血清钙、磷和锌水平均明显低于轻度DR 组,骨碱性磷酸酶亦明显高于后者(P均<0.05)。 【结论】 骨碱性磷酸酶结合血清钙、磷、锌水平是反映佝偻病病情的敏感指标。
Abstract
【Objective】 To compare the levels of the serum calcium,phosphorus,zinc and bone alkaline phosphatase in 60 different rickets (DR) children with those in 60 cases of healthy children. 【Methods】 All the children were selected in Guangzhou during the same period.The 60 rickets children were divided into three groups according to the severity. 【Results】 The levels of calcium,phosphorus and zinc in moderate and severe DR group were significantly lower than that in the control group;the DR group bone alkaline phosphate level was significantly higher than the healthy group's.(P<0.05).Compared with the mild DR group,moderate and severe DR group had significantly less peripheral blood calcium,phosphorus and zinc,and more bone alkaline phosphatase (P<0.05). 【Conclusion】 Serum bone alkaline phosphatase,combining with the serum calcium,phosphorus,zinc,is a sensitive indicator of the disease rickets.
关键词
血清钙、磷、锌元素 /
骨碱性磷酸酶 /
佝偻病
Key words
serum calcium,phosphorus,zinc /
bone alkaline phosphatase /
rickets
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参考文献
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