【目的】 研究儿童阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)中的危险性因素,并探讨肥胖、扁桃体肥大及腺样体肥大与儿童OSAHS的相关性。 【方法】 对182例儿童OSAHS患者及160例无OSAHS儿童进行体质指数(body mass index,BMI)、扁桃体大小及腺样体大小进行评价。对全部儿童进行多导睡眠监测(polysomnography,PSG),以无OSAHS儿童作为对照组。 【结果】 患有OSAHS儿童的体质指数、扁桃体肿大程度及腺样体肥大显著高于对照组儿童,并且两组患儿的OSA评分、呼吸暂停指数、最低血氧饱和度的差异有统计学意义(P<0.05)。 【结论】 儿童OSAHS严重影响儿童的生活质量,肥胖、扁桃体肥大以及腺样体肥大均是儿童OSAHS的危险因素。可以通过从病因着手控制儿童OSAHS的发生。
Abstract
【Objective】 To study the dangerous factors in children with obstructive sleep apnea hypopnea syndrome(OSAHS),and to explore whether obesity and the tonsil and/or adenoid hypertrophy would cause obstructive sleep apnea hypopnea syndrome. 【Methods】 The body mass index(BMI) and the tonsil and adenoid size were evaluated on 182 OSAHS and 160 non-OSAHS children.All children were examined by polysomnography(PSG). 【Results】 Among OSAHS,BMI and the tonsil and adenoid size were significantly higher than the control group of children's.In addition,OSA score and apnea hypopnea index(AHI),LSaO2 showed a positive correlation.Obesity,tonsillar hypertrophy,and adenoid hypertrophy were the dangerous factors for OSAHS. 【Conclusion】 OSAHS had impact on children's quality of life seriously.It indicated that there were certain relations between pathogenetic factors and obesity,tonsillar hypertrophy and adenoid hypertrophy.we can pass from the etiology to control the occurrence of OSAHS in children.
关键词
阻塞性睡眠呼吸暂停低通气综合征 /
体质指数 /
扁桃体 /
腺样体 /
儿童
Key words
obstructive sleep apnea hypopnea syndrome /
body mass index /
tonsil /
adenoid /
child
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参考文献
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基金
山东省科技厅星火计划项目(2009XH111)
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