【目的】 了解铅对儿童视力、立体视及视觉诱发电位有无影响,为防治其对儿童视功能发育的损害提供科学依据。 【方法】 随机选择4~10岁的儿童172例,检测血清铅浓度,按正常和超过正常分为正常血铅组和高血铅组。并分别比较两组间矫正视力、立体视锐度及视觉诱发电位的差异。 【结果】 高血铅组矫正视力异常人数与血铅正常组相比,差异有高度统计学意义(P<0.01);两组间P100潜伏期及矫正立体视锐度比较差异有统计学意义(P<0.05);两组间P100振幅比较差异无统计学意义(P>0.05)。 【结论】 高血铅对儿童视力、立体视及视觉诱发电位都有不利影响,需重视防治铅污染及其导致的儿童视功能发育异常。
Abstract
【Objective】 To find out the influences of high blood lead level on visual acuity,stereoacuity,visual evoked potentials in children. 【Method】 172 children aged 4 to 10 were randomly selected and their serum concentration of lead were detected.They were divided into normal blood lead group and high blood lead group by the blood lead level. 【Results】 The difference of cases with abnormal corrected visual acuity between high blood lead group and normal blood lead group was statistically significant(P<0.01).P100 latency was significantly delayed and the difference of P100 latency and stereoacuity were statistically significant between two groups(P<0.05).P100 amplitudes did not differ significantly from the normal group(P>0.05). 【Conclusions】 High blood lead level has bad influence on visual acuity,stereoacuity,visual evoked potentials in children.More attention should be paid to the prevention of the lead pollution and the abnormal development of visual function.
关键词
铅 /
视力 /
立体视 /
视觉诱发电位
Key words
lead /
visual acuity /
stereoacuity /
visual evoked potential
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参考文献
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基金
广东省卫生厅科研基金资助(B2001025)