【目的】 通过皮肤点刺试验(skin prick tests,SPT)对湿疹婴儿进行食物过敏原的检测,评价其临床意义。 【方法】 对170名4~12月湿疹婴儿进行六种食物过敏原的皮肤点刺试验,并根据阳性结果进行敏感食物回避8周,并对比食物回避前后的皮肤症状。 【结果】 170名湿疹婴儿中,118名(69.41%)SPT存在阳性结果,阳性食物依次为蛋清(42.35%)、蛋黄 (36.47%)、牛奶(27.06%)、带鱼(18.82%)、海虾(17.65%)、大豆(9.41%)。敏感食物回避8周后,90.68%的患儿皮肤症状缓解。 【结论】 湿疹婴儿多数存在食物过敏,敏感食物回避效果明显。SPT特异性高,方法简单,对湿疹患儿的食物过敏诊断和治疗意义重大。
Abstract
【Objective】 To assess the clinical application of skin prick tests of food allergens in infants with eczema. 【Methods】 170 infants aged 4~12 months suffered from eczema were involved in this study. Skin prick tests of six food allergens were analyzed. Dietary prevention were applied in infants with positive results for 8 weeks, and compared the skin symptoms. 【Results】 The overall positive rate was 69.71%. The positive rate from high to low were egg white(42.35%), egg yolk (36.47%), cow milk(27.06%), ribbon fish(18.82%),prawn(17.65%),soybean(9.41%). After 8 weeks of dietary prevention, obvious remission of the skin symptoms were found in 90.68% infants. 【Conclusions】 Most infants with eczema have food allergy. The avoidance of offending food is a effective treatment. SPT is important to diagnosis and treatment of food allergy in infants with eczema.
关键词
湿疹 /
食物过敏 /
皮肤点刺试验 /
婴儿
Key words
eczema /
food allergy /
skin prick test /
infant
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