儿童高尿酸血症与代谢综合征的关联机制及治疗进展

刘佩佩; 董国庆; 陆喜燕; 李明珠; 黄秒

doi:10.11852/zgetbjzz2026-0110

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中国儿童保健杂志 ›› 2026, Vol. 34 ›› Issue (10) : 1164-1167. DOI: 10.11852/zgetbjzz2026-0110

综述

儿童高尿酸血症与代谢综合征的关联机制及治疗进展

刘佩佩, 董国庆, 陆喜燕, 李明珠, 黄秒

作者信息 +

Mechanisms linking hyperuricemia and metabolic syndrome in children and advances in treatment

LIU Peipei, DONG Guoqing, LU Xiyan, LI Mingzhu, HUANG Miao

Author information +

文章历史 +

摘要

儿童高尿酸血症(HUA)与代谢综合征(MetS)是儿科内分泌代谢领域日益受到关注的健康问题。两者常并存且可能相互促进,从而增加儿童期及远期心血管代谢疾病风险。本文综述儿童HUA与MetS的流行病学特征、共同病理生理机制、临床关联和治疗进展,旨在为高危儿童的早期识别及以生活方式干预和药物治疗为基础的综合管理提供理论依据与实践参考。

Abstract

Hyperuricemia (HUA) and metabolic syndrome (MetS) in children are increasingly recognized as important concerns in pediatric endocrinology and metabolism. The two conditions frequently coexist and may reinforce each other, thereby increasing cardiometabolic risk during childhood and later life. This review summarizes the epidemiological characteristics, shared pathophysiological mechanisms, clinical associations, and treatment advances of pediatric HUA and MetS, in order to provide a theoretical basis and practical reference for the early identification of high-risk children and comprehensive management centered on lifestyle interventions and pharmacological therapy.

导出引用

刘佩佩, 董国庆, 陆喜燕, 李明珠, 黄秒. 儿童高尿酸血症与代谢综合征的关联机制及治疗进展[J]. 中国儿童保健杂志. 2026, 34(10): 1164-1167 https://doi.org/10.11852/zgetbjzz2026-0110

LIU Peipei, DONG Guoqing, LU Xiyan, LI Mingzhu, HUANG Miao. Mechanisms linking hyperuricemia and metabolic syndrome in children and advances in treatment[J]. Chinese Journal of Child Health Care. 2026, 34(10): 1164-1167 https://doi.org/10.11852/zgetbjzz2026-0110

中图分类号： R179

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