基于磁共振成像的发展性阅读障碍儿童脑结构与功能特征研究

吴影慧; 张琴芬

doi:10.11852/zgetbjzz2025-1022

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中国儿童保健杂志 ›› 2026, Vol. 34 ›› Issue (11) : 1279-1283. DOI: 10.11852/zgetbjzz2025-1022

综述

基于磁共振成像的发展性阅读障碍儿童脑结构与功能特征研究

吴影慧, 张琴芬

作者信息 +

Magnetic resonance imaging-based structural and functional brain characteristics in children with developmental dyslexia

WU Yinghui, ZHANG Qinfen

Author information +

文章历史 +

摘要

发展性阅读障碍是儿童期常见的神经发育障碍,严重影响个体的学业与社会功能。磁共振成像(MRI)作为非侵入性神经影像技术,近年来广泛应用于其神经机制及干预效应的研究中。本文综述了国内外关于阅读障碍儿童的结构MRI与功能MRI研究进展,重点涉及阅读相关脑区的灰质、白质改变特征,静息态与任务态功能连接模式,以及干预前后的神经可塑性变化。采用多模态MRI与人工智能辅助分析的结合,为发展性阅读障碍的早期识别与精准干预提供了新的方向。当前研究尚存在样本代表性不足、方法标准不统一、结果重复性较差等问题。未来应加强多中心协作、纵向追踪与多模态融合研究,推动神经影像学在儿童发展性阅读障碍中的临床转化与实践应用。

Abstract

Developmental dyslexia is a common childhood neurodevelopmental disorder that substantially affects academic performance and social functioning. Magnetic resonance imaging (MRI), a noninvasive neuroimaging technique, has been widely used in recent years to investigate its neural mechanisms and the effects of intervention. This review summarizes recent structural and functional MRI findings in children with developmental dyslexia, with emphasis on gray- and white-matter alterations in reading-related brain regions, resting-state and task-based functional connectivity, and intervention-related neuroplastic changes. Integrating multimodal MRI with artificial intelligence-assisted analysis may facilitate early identification and individualized intervention. However, current studies are limited by inadequate sample representativeness, a lack of methodological standardization, and limited reproducibility. Future research should prioritize multicenter collaboration, longitudinal follow-up, and multimodal integration to facilitate the clinical translation and application of neuroimaging in childhood developmental dyslexia.

导出引用

吴影慧, 张琴芬. 基于磁共振成像的发展性阅读障碍儿童脑结构与功能特征研究[J]. 中国儿童保健杂志. 2026, 34(11): 1279-1283 https://doi.org/10.11852/zgetbjzz2025-1022

WU Yinghui, ZHANG Qinfen. Magnetic resonance imaging-based structural and functional brain characteristics in children with developmental dyslexia[J]. Chinese Journal of Child Health Care. 2026, 34(11): 1279-1283 https://doi.org/10.11852/zgetbjzz2025-1022

中图分类号： R179

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