生命早期肠道菌群特征与婴幼儿神经发育相关性的研究进展

魏鑫鑫; 赵岩; 吕智海; 陈世动; 缪芸

doi:10.11852/zgetbjzz2025-0980

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中国儿童保健杂志 ›› 2026, Vol. 34 ›› Issue (11) : 1274-1278. DOI: 10.11852/zgetbjzz2025-0980

综述

生命早期肠道菌群特征与婴幼儿神经发育相关性的研究进展

魏鑫鑫^1,2, 赵岩², 吕智海², 陈世动¹, 缪芸¹

作者信息 +

Advances in the correlation between early-life gut microbiota characteristics and neurodevelopment in infants and young children

WEI Xinxin^1,2 , ZHAO Yan², LÜ Zhihai², CHEN Shidong¹, MIAO Yun¹

Author information +

文章历史 +

摘要

生命早期肠道菌群是调控婴幼儿神经发育的关键生物组成部分,其影响始于生命初期并持续终生。了解肠道微生物组如何通过关键菌群影响婴幼儿神经认知行为以及大脑结构、功能,是当前肠-脑轴研究领域的核心前沿与挑战。本文总结了儿童肠道菌群特征与神经发育的关系,旨在挖掘潜在的临床生物标志物,为婴幼儿神经发育障碍的预测及治疗提供新的思路和方向。

Abstract

The early-life gut microbiota is a crucial biological determinant of neurodevelopment in infants and young children, exerting effects that initiate in early life and persist throughout the lifespan.Understanding how the gut microbiota influences neurocognitive behavior and brain structure/function via key microbial communities represents a major frontier and challenge in gut-brain axis research.This review summarizes the relationship between infant gut microbiota characteristics and neurodevelopment, with the aim of identifying potential clinical biomarkers and providing new insights and directions for predicting and treating neurodevelopmental disorders.

导出引用

魏鑫鑫, 赵岩, 吕智海, 陈世动, 缪芸. 生命早期肠道菌群特征与婴幼儿神经发育相关性的研究进展[J]. 中国儿童保健杂志. 2026, 34(11): 1274-1278 https://doi.org/10.11852/zgetbjzz2025-0980

WEI Xinxin , ZHAO Yan, LÜ Zhihai, CHEN Shidong, MIAO Yun. Advances in the correlation between early-life gut microbiota characteristics and neurodevelopment in infants and young children[J]. Chinese Journal of Child Health Care. 2026, 34(11): 1274-1278 https://doi.org/10.11852/zgetbjzz2025-0980

中图分类号： R179

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