细胞生物力学视角下的儿童肥胖研究进展

彭舟; 王晓雨; 郭锡熔

doi:10.11852/zgetbjzz2025-0303

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中国儿童保健杂志 ›› 2025, Vol. 33 ›› Issue (10) : 1086-1090. DOI: 10.11852/zgetbjzz2025-0303

儿童代谢性疾病专栏

细胞生物力学视角下的儿童肥胖研究进展

彭舟^1,2, 王晓雨³, 郭锡熔^1,2

作者信息 +

Research progress of pediatric obesity from the perspective of cellular biomechanics

PENG Zhou^1,2, WANG Xiaoyu³, GUO Xirong^1,2

Author information +

文章历史 +

摘要

近年来细胞生物力学在肥胖防治中的研究逐渐受到关注。儿童肥胖是成年代谢性疾病早期关键的防治窗口,细胞生物力学可为儿童肥胖的防治提供新的可能。传统上主要聚焦于宏观层面的运动力学,而近年来的研究已进一步深入至细胞和分子水平。为了解细胞生物力学下儿童肥胖研究进展,以细胞生物力学和儿童肥胖为检索词,通过计算机系统检索PubMed、Web of Science及CNKI等数据库,检索时限为2011—2025年,纳入近五年文献率90%以上。本文通过介绍生物力学作用元件,总结饮食运动管理和遗传因素相关的细胞生物力学研究成果,并对细胞生物力学视角下儿童肥胖的未来发展进行了展望,以期为儿童肥胖的研究拓展研究思路,提供参考。

Abstract

In recent years, cellular biomechanics has gained increasing attention in the field of obesity prevention and management.Childhood obesity serves as a critical early intervention window for preventing adult metabolic diseases, and cellular biomechanics may offer novel strategies for addressing this issue.Traditionally, research has focused on macro-level exercise mechanics, but recent studies have delved deeper into cellular and molecular mechanisms.To explore advances in childhood obesity research from a cellular biomechanics perspective, a systematic search was conducted in PubMed, Web of Science, and CNKI databases using keywords such as cellular biomechanics and childhood obesity, covering publications from 2011 to 2025, with over 90% of the included literature from the past five years.This review introduces key biomechanical elements, summarizes findings related to dietary and exercise interventions as well as genetic factors, and discusses future directions for childhood obesity research from a cellular biomechanics standpoint.By exploring these insights, this article aims to inspire new research approaches and serve as a valuable resource for understanding pediatric obesity from a cellular biomechanic perspective.

导出引用

彭舟, 王晓雨, 郭锡熔. 细胞生物力学视角下的儿童肥胖研究进展[J]. 中国儿童保健杂志. 2025, 33(10): 1086-1090 https://doi.org/10.11852/zgetbjzz2025-0303

PENG Zhou, WANG Xiaoyu, GUO Xirong. Research progress of pediatric obesity from the perspective of cellular biomechanics[J]. Chinese Journal of Child Health Care. 2025, 33(10): 1086-1090 https://doi.org/10.11852/zgetbjzz2025-0303

中图分类号： R174

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