家庭干预治疗脑性瘫痪儿童疗效的Meta分析

房恩慧; 管惠; 田金鑫; 张浩; 马丽虹

doi:10.11852/zgetbjzz2024-1104

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中国儿童保健杂志 ›› 2025, Vol. 33 ›› Issue (12) : 1358-1366. DOI: 10.11852/zgetbjzz2024-1104

荟萃分析

家庭干预治疗脑性瘫痪儿童疗效的Meta分析

房恩慧¹, 管惠¹, 田金鑫¹, 张浩¹, 马丽虹^1,2

作者信息 +

Meta-analysis on the efficacy of family interventions for children with cerebral palsy

FANG Enhui¹, GUAN Hui¹, TIAN Jinxin¹, ZHANG Hao¹, MA Lihong^1,2

Author information +

文章历史 +

摘要

目的系统评价家庭干预对脑瘫儿童粗大运动功能及日常生活活动能力的疗效,为制定有效的干预策略提供依据。方法检索知网、维普、万方、CBM、PubMed、Embase、Web of Science、Cochrane Library中家庭干预治疗脑瘫儿童的研究文献,时限为建库至2024年6月。采用Review Manager 5.4和Stata17.0进行Meta分析。结果最终纳入28篇文献,Meta分析结果显示,家庭干预组与常规康复组GMFM-88评分(MD=10.87,95%CI:8.51~13.23)、GMFM-88 E区评分(MD=4.71,95%CI:3.82~5.61)、ADLs评分(MD=7.63,95%CI:4.68~10.57)差异有统计学意义(P<0.001),两组儿童GMFM-66评分差异无统计学意义(MD=4.43,95%CI:-1.56~10.42,P=0.15)。结论家庭干预能够有效改善脑瘫儿童粗大运动功能及日常生活活动能力。

Abstract

Objective To systematically evaluate the efficacy of home-based interventions in improving gross motor function and activities of daily living (ADL) in children with cerebral palsy (CP), so as to provide evidence for developing effective intervention strategies. Methods Literature on home-based interventions for children with CP were searched across databases including CNKI, VIP, Wanfang, CBM, PubMed, Embase, Web of Science, and Cochrane Library from inception to June 2024.Meta-analysis was performed using Review Manager 5.4 and Stata 17.0. Results A total of 28 studies were included.Meta-analysis revealed statistically significant differences between the home-based intervention group and conventional rehabilitation group in GMFM-88 scores (MD=10.87, 95% CI: 8.51 - 13.23), GMFM-88 E dimension scores (MD=4.71, 95% CI: 3.82 - 5.61), and ADLs scores (MD=7.63, 95% CI: 4.68 - 10.57) (P<0.001).However, no significant difference was observed in GMFM-66 scores (MD=4.43, 95% CI: －1.56 - 10.42, P=0.15)between the two groups. Conclusion Home-based interventions can effectively improve gross motor function and ADL performance in children with cerebral palsy.

导出引用

房恩慧, 管惠, 田金鑫, 张浩, 马丽虹. 家庭干预治疗脑性瘫痪儿童疗效的Meta分析[J]. 中国儿童保健杂志. 2025, 33(12): 1358-1366 https://doi.org/10.11852/zgetbjzz2024-1104

FANG Enhui, GUAN Hui, TIAN Jinxin, ZHANG Hao, MA Lihong. Meta-analysis on the efficacy of family interventions for children with cerebral palsy[J]. Chinese Journal of Child Health Care. 2025, 33(12): 1358-1366 https://doi.org/10.11852/zgetbjzz2024-1104

中图分类号： R179

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