小于胎龄儿的营养干预研究进展

包姝沄, 邢燕

中国儿童保健杂志 ›› 2023, Vol. 31 ›› Issue (10) : 1116-1120.

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中国儿童保健杂志 ›› 2023, Vol. 31 ›› Issue (10) : 1116-1120. DOI: 10.11852/zgetbjzz2022-1062
综述

小于胎龄儿的营养干预研究进展

  • 包姝沄1, 邢燕2
作者信息 +

Research progress in nutrition intervention of small for gestational age infants

  • BAO Shuyun1, XING Yan2
Author information +
文章历史 +

摘要

小于胎龄(SGA)儿属于新生儿中的一类特殊群体,其发生主要与胎儿、胎盘及母体因素有关。SGA儿可能出现早期体格生长发育迟缓,其远期代谢综合征、认知功能障碍等疾病的发生风险亦会增加。对SGA儿进行适度的营养干预可促进其早期合理生长与良好的神经发育,但过度的营养强化又与一系列代谢性疾病、心血管疾病等相关。因此,如何衡量营养干预与过度强化之间的关系,实现SGA儿的最适追赶生长是临床研究的热点。现就SGA儿的营养需求、营养支持、喂养策略等内容进行综述。

Abstract

Small for gestational age (SGA) infants is a special group of neonates.The occurrence of SGA is mainly related to fetal, placental and maternal factors.SGA infants may have early physical growth retardation, and its long-term risk of metabolic syndrome, cognitive dysfunction and other diseases will also increase.Moderate nutritional intervention on SGA infants can promote its early reasonable growth and good neural development, but excessive nutritional fortification is associated with a series of metabolic diseases, cardiovascular diseases and so on.Therefore, balancing the relationship between nutritional intervention and excessive reinforcement to achieve the optimal catch-up growth of SGA infants is a hot topic in clinical research.This article reviews the nutritional requirements, nutritional support and feeding strategies of SGA infants.

关键词

小于胎龄儿 / 营养干预 / 喂养策略

Key words

small for gestational age infants / nutrition intervention / feeding strategy

引用本文

导出引用
包姝沄, 邢燕. 小于胎龄儿的营养干预研究进展[J]. 中国儿童保健杂志. 2023, 31(10): 1116-1120 https://doi.org/10.11852/zgetbjzz2022-1062
BAO Shuyun, XING Yan. Research progress in nutrition intervention of small for gestational age infants[J]. Chinese Journal of Child Health Care. 2023, 31(10): 1116-1120 https://doi.org/10.11852/zgetbjzz2022-1062
中图分类号: R153.1   

参考文献

[1] Boguszewski MC, Mericq V, Bergada I, et al.Latin American consensus: Children born small for gestational age[J].BMC pediatrics, 2011(11):66.
[2] Lee AC, Katz J, Blencowe H, et al.National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010[J].Lancet Glob Health, 2013, 1(1):e26-36.
[3] Rotem R, Rottenstreich M, Prado E, et al.Trends of change in the individual contribution of risk factors for small for gestational age over more than 2 decades[J].Arch Gynecol Obstet, 2020, 302(5):1159-1166.
[4] 杜敏联, 傅君芬.对生长迟缓和生长追赶的再认识[J].中华儿科杂志, 2022, 60(3):173-176.
Du ML, Fu JF.Reconsideration of growth retardation and growth catch-up[J].Chin J Pediatr, 2022, 60(3):173-176.(in Chinese)
[5] Huang L, Yang S, Yang F, et al.A prospective study about physical growth of children from birth to 2 years old born full-term small-for-gestational-age[J].J Paediatr Child Health, 2019, 55(2):199-204.
[6] Campisi SC, Carbone SE, Zlotkin S.Catch-up growth in full-term small for gestational age infants:A systematic review[J].Adv Nutr, 2019, 10(1):104-111.
[7] Zhao Y, Fan X, Wen J, et al.Analysis of longitudinal follow-up data of physical growth in singleton full-term small for gestational age infants[J].J Int Med Res, 2021, 49(12):03000605211060672.
[8] Cunha LPM, Cecília Santiago A, Florence T, et al.Birth weight for gestational age, recovery of growth and anthropometric profile of pre-school children born full term:A follow-up study[J].Pediatr Endocrinol Diabetes Metab, 2021, 27(1):26-31.
[9] Murki S, Kallem VR, Gururaj J, et al.Growth and neurodevelopmental outcomes at 12 to 18 months of corrected age in preterm infants born small for gestational age[J].Indian Pediatr, 2020, 57(4):301-304.
[10] Wu D, Zhu J, Wang X, et al.Rapid BMI increases and persistent obesity in small-for-gestational-age infants[J].Front Pediatr, 2021, 9:625853.
[11] Abranches AD, Soares FVM, Villela LD, et al.Energy expenditure, growth, and nutritional therapy in appropriate and small for gestational age preterm infants[J].J Pediatr (Rio J), 2018, 94(6):652-657.
[12] Alsweiler JM, Harris DL, Harding JE, et al.Strategies to improve neurodevelopmental outcomes in babies at risk of neonatal hypoglycaemia[J].Lancet Child Adolesc Health 2021, 5(7):513-523.
[13] Edwards T, Liu G, Hegarty JE, et al.Oral dextrose gel to prevent hypoglycaemia in at-risk neonates[J].Cochrane Database Syst Rev, 2021, 5(5):Cd012152.
[14] Amissah EA, Brown J, Harding JE.Fat supplementation of human milk for promoting growth in preterm infants[J].Cochrane Database Syst Rev, 2018, 6(6):Cd000341.
[15] Rabinowicz S, Levkovitz O, Leibovitch L, et al.Increased risk for early hypertriglyceridemia in small for gestational age preterm infants[J].Eur J Pediatr, 2020, 179(12):1873-1879.
[16] Castillo F, Castillo-Ferrer FJ, Cordobilla B, et al.Inadequate content of docosahexaenoic acid (DHA) of donor human milk for feeding preterm infants:A comparison with mother's own milk at different stages of lactation[J].Nutrients, 2021,13(4):1300.
[17] Maguolo A, Olivieri F, Zusi C, et al.The risk of metabolic derangements is higher in children and adolescents with overweight or obesity born small for gestational age[J].Nutr Metab Cardiovasc Dis, 2021, 31(6):1903-1910.
[18] Wall CR, Murphy R, Waldie KE, et al.Dietary intakes in children born small for gestational age and appropriate for gestational age:A longitudinal study[J].Matern Child Nutr, 2017, 13(4):e12373.
[19] Beken S, Abali S, Yildirim Saral N, et al.Early postnatal metabolic profile in neonates with different birth weight status:A pilot study[J].Front Pediatr, 2021(9):646860.
[20] Staub E, Evers K, Askie LM.Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates[J].Cochrane Database Syst Rev, 2021, 3(3):Cd012797.
[21] 李彩梅, 丁晓春.小于胎龄儿出生后血清维生素B12及脑发育水平研究[J].中华临床医师杂志(电子版), 2020, 14(5):370-375.
Li CM, Ding XC.Serum vitamin B12 and brain development levels in small for gestational age infants[J].Chin J Clinicians(Electronic Edition), 2020, 14(5):370-375.(in Chinese)
[22] Tudehope D, Vento M, Bhutta Z, et al.Nutritional requirements and feeding recommendations for small for gestational age infants[J].J Pediatr, 2013, 162(Suppl 3):81-89.
[23] Ahmed F, Dey SK, Shahidullah M, et al.Early versus delayed enteral feeding for achieving full feeding in preterm growth-restricted infants:A randomized clinical trial[J].Mymensingh Med J, 2020, 29(3):638-645.
[24] Fallon EM, Nehra D, Potemkin AK, et al.A.S.P.E.N.clinical guidelines:Nutrition support of neonatal patients at risk for necrotizing enterocolitis[J].JPEN J Parenter Enteral Nutr, 2012, 36(5):506-523.
[25] 杨琴, 程茜, 张萱.足月小于胎龄儿6月龄内能量摄入与追赶生长的关系[J].中华儿科杂志, 2015, 53(12):919-924.
Yang Q, Cheng Q, Zhang X.Relationship between energy intake and catch-up growth in full-term small-for-gestational-age infants under 6 months of age[J].Chin J Pediatr, 2015, 53(12):919-924.(in Chinese)
[26] Meek JY, Noble L.Technical report:Breastfeeding and the use of human milk[J].Pediatrics, 2022, 150(1):e2022057989.
[27] Nurani N, Wibowo T, Susilowati R, et al.Growth of exclusively breastfed small for gestational age term infants in the first six months of life:A prospective cohort study[J].BMC Pediatr, 2022, 22(1):73.
[28] Castagno M, Menegon V, Monzani A, et al.Small-for-gestational-age birth is linked to cardiovascular dysfunction in early childhood[J].Am Heart J, 2019(217):84-93.
[29] Visuthranukul C, Abrams SA, Hawthorne KM, et al.Premature small for gestational age infants fed an exclusive human milk-based diet achieve catch-up growth without metabolic consequences at 2 years of age[J].Arch Dis Child Fetal Neonatal Ed, 2019, 104(3):F242-F247.
[30] Santiago ACT, Da Cunha LPM, Costa ML, et al.Cardiometabolic evaluation of small for gestational age children:Protective effect of breast milk[J].Nutr Hosp, 2021, 38(1):36-42.
[31] Fleig L, Hagan J, Lee ML, et al.Growth outcomes of small for gestational age preterm infants before and after implementation of an exclusive human milk-based diet[J].J Perinatol, 2021, 41(8):1859-1864.
[32] Perrin MT, Belfort MB, Hagadorn JI, et al.The nutritional composition and energy content of donor human milk:A systematic review[J].Adv Nutr, 2020, 11(4):960-970.
[33] Gao C, Miller J, Collins CT, et al.Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological development in preterm infants[J].Cochrane Database Syst Rev, 2020, 11(11):Cd007090.
[34] Quigley M, Embleton ND, Mcguire W.Formula versus donor breast milk for feeding preterm or low birth weight infants[J].Cochrane Database Syst Rev, 2019, 7(7):Cd002971.
[35] Toftlund LH, Halken S, Agertoft L, et al.Catch-up growth, rapid weight growth, and continuous growth from birth to 6 years of age in very-preterm-born children[J].Neonatology, 2018, 114(4):285-293.
[36] Brownell EA, Matson AP, Smith KC, et al.Dose-response relationship between donor human milk, mother's own milk, preterm formula, and neonatal growth outcomes[J].J Pediatr Gastroenterol Nutr, 2018, 67(1):90-96.
[37] Lei X, Chen Y, Ye J, et al.The optimal postnatal growth trajectory for term small for gestational age babies:A prospective cohort study[J].J Pediatr, 2015, 166(1):54-58.

基金

国家重点研发计划 (2021YFC2700700);中华国际医学交流基金会中国儿童生长发育学术交流专项基金(Z-2019-41-2101-01)

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