目的 探讨悬吊疗法联合MOTOmed智能训练对痉挛性脑瘫患儿的临床疗效,以期为临床完善相关干预方案提供参考。方法 选取2020年5月-2021年5月来河北省儿童医院诊治且确认为痉挛型脑瘫患儿150例,使用随机数字表法将患儿分为观察组与对照组,每组各75例。对照组采用MOTOmed智能训练,观察组在此基础上加入悬吊疗法。连续干预8周,比较两组患儿治疗前后的躯干控制能力、Berg量表评分、粗大运动功能评估表(GMFM)及改良Barthel指数(MBI) 评分和血清神经生长因子 (NGF)及内皮素(ET)水平。结果 治疗后,观察组躯干总标准差、躯干前后标准差、躯干左右标准差低于对照组,差异具有统计学意义(t=2.992、6.860、8.380,P<0.05);观察组Berg评分、GMFM评分、MBI评分高于对照组,差异具有统计学意义(t=2.192、2.126、2.331,P<0.05);观察组NGF水平高于对照组,ET水平低于对照组,差异具有统计学意义(t=3.560、2.806,P<0.05)。结论 悬吊疗法联合MOTOmed智能训练可有效改善患儿的躯干控制能力,促进其粗大运动发育,改善患儿的平衡功能和日常生活活动能力,且效果优于单一的MOTOmed智能训练治疗,可在临床中推广应用。
Abstract
Objective To explore the clinical effect of suspension therapy combined with MOTOmed intelligent training in children with spastic cerebral palsy, in order to provide reference for clinical improvement of related intervention programs. Methods A total of 150 children with spastic cerebral palsy and treated in Children's Hospital of Hebei Province from May 2020 to May 2021 were included and divided into observation group and control group by random number table, with 75 cases in each group.The control group received MOTOmed intelligent training, and the observation group received suspension therapy additionally.The intervention lasted for 8 weeks.Trunk control ability, Berg Scale Score, Gross Motor Function Measure(GMFM) and Modified Barthel Index(MBI) score, serum nerve growth factor(NGF) and endothelin(ET) level were compared between the two groups before and after treatment. Results After treatment, the total trunk control ability, the front and back trunk control ability, the left and right trunk control ability of the observation group were significantly lower than those of the control group (t=2.992, 6.860, 8.380,P<0.05).The Berg score, GMFM score, MBI score of the observation group were higher than those of the control group, and the difference was statistically significant (t=2.192, 2.126, 2.331, P<0.05).The level of NGF in the observation group was higher than that of the control group, while the level of ET was lower than that of the control group, and the difference was statistically significant (t=3.560, 2.806, P<0.05). Conclusions Suspension therapy combined with MOTOmed intelligent training can effectively improve children's trunk control ability, promote their gross motor development, improve children's balance function and activities of daily living.Moreover, the combined efficacy is better than that of MOTOmed intelligent training alone, which can be popularized and applied in clinic.
关键词
痉挛型脑瘫 /
悬吊疗法 /
躯干控制 /
平衡功能 /
粗大运动
Key words
spastic cerebral palsy /
suspension therapy /
trunk control /
balance function /
gross motor
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基金
河北省医学科学研究重点课题计划(20180619)