人体内的营养性微量金属元素,主要依靠肠道吸收,在各种生命活动中起着非常重要的作用。本文总结了近年来铁、锌、铜、锰、钼、铬、钴等常见微量金属元素在肠道内吸收机制的研究进展,并探索元素吸收间的相互作用形式。金属元素在机体内通过吸收、分布、排泄维持稳态,整个过程都依赖机体的代谢调节。因此,影响微量金属元素在肠道吸收的因素,不仅是膳食中金属元素间的相互干扰,还包括金属元素的化学形态、金属元素间的比例、食物中其他与金属元素共存的成分、肠道菌群等,更重要的是机体状态。本文将在此基础上提出临床营养补充策略。
Abstract
The nutritive trace metal elements in the human body are mainly absorbed by the intestine and play a very important role in various life activities.This article summarizes the recent research progress in the intestinal absorption mechanism of common trace elements, such as iron, zinc, copper, manganese, molybdenum, chromium and cobalt, and explores the forms of interaction between element absorption.Metal elements in the body maintain a steady state through absorption, distribution and excretion, and the whole process requires the body′s overall metabolic regulation.Therefore, the factors that affect the absorption of trace metal elements in the intestine are not only the interference between the metal elements in the diet, but also the chemical form of the metal elements, the ratio of metal elements, other coexisting components in the food, and the intestinal flora, etc.More important is the state of the body.This article will propose clinical nutritional supplement strategies on this basis.
关键词
微量元素 /
金属元素 /
肠道吸收机制 /
金属元素代谢
Key words
trace elements /
metal elements /
intestinal absorption mechanism /
metal element metabolism
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基金
国家重点研发基金项目(2017YFC1600500)
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