目的 探讨我国儿童青少年不同肥胖类型对血压偏高的相加交互作用,为有效控制血压水平提供依据。方法 研究数据来自于2012年中国七个省市的儿童青少年的横断面调查。采用多阶段整群抽样的方法,连续变量和分类变量分别采用t检验和χ2检验分析变量之间的组间差异。采用Logistic回归分析不同肥胖类型和血压偏高之间的关联,分析一般性肥胖和单纯性腹型肥胖之间的交互作用。结果 本研究共纳入40 015名儿童青少年,一般性肥胖、单纯腹型肥胖和复合型肥胖儿童青少年血压偏高的比例分别为17.7%、12.0%和23.2%。复合型肥胖对男生和城市儿童青少年血压偏高的影响较大(男生OR=2.80,95%CI:2.55~3.07;城市OR=2.95,95%CI:2.69~3.24 ),收缩压和舒张压偏高呈现相同结果。在儿童青少年血压偏高的人群中,由一般性肥胖和单纯腹型肥胖的相加交互作用所引起的血压偏高的比例占22%。结论 一般性肥胖比单纯腹型肥胖对血压的影响更大,在不同肥胖类型中,复合型肥胖仍然是导致血压偏高最危险的因素。在儿童青少年血压偏高的人群中,一般性肥胖和单纯腹型肥胖具有相加交互作用。
Abstract
Objective To investigate the additive interaction of different types of obesity on high blood pressure in children and adolescents,in order to provide basis for controlling blood pressure level effectively. Methods Data were collected from a cross-sectional survey of children and adolescents with a multi-stage cluster sampling in seven provinces and cities in China in 2012. T test and chi-square test were used to analyze the differences between continuous variables and classified variables,respectively. Logistics regression was used to analyze the correlation between different types of obesity and high blood pressure,and the interaction between general obesity and simple abdominal obesity was analyzed. Results A total of 40 015 children and adolescents were included in this study. The proportion of children with general obesity,simple abdominal obesity and compound obesity with high blood pressure was 17.7%,12.0% and 23.2%,respectively. Compound obesity had a greater effect on high blood pressure in boys and urban children and adolescents (boys OR=2.80,95%CI: 2.55—3.07; urban OR=2.95,95%CI: 2.69-3.24),the same results were found for the high systolic and diastolic blood pressure. In children and adolescents with high blood pressure,the additive interaction of general obesity and simple abdominal obesity caused the high blood pressure in 22% of the population. Conclusions General obesity has a greater effect on blood pressure than simple abdominal obesity. Among different types of obesity,compound obesity is still the most risk factor leading to high blood pressure. In children and adolescents with high blood pressure,general obesity and simple abdominal obesity have additive interaction.
关键词
儿童青少年 /
肥胖类型 /
血压偏高 /
交互作用
Key words
children and adolescents /
types of obesity /
high blood pressure /
interaction
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基金
博士后科学基金(BX20200019;2020M680266)
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