孤独症谱系障碍儿童睡眠障碍的评估和干预

陈岑; 程慧; 江帆; 沈敏; 王广海

doi:10.11852/zgetbjzz2021-0195

PDF(689 KB)

中国儿童保健杂志 ›› 2022, Vol. 30 ›› Issue (6) : 637-641. DOI: 10.11852/zgetbjzz2021-0195

综述

孤独症谱系障碍儿童睡眠障碍的评估和干预

陈岑¹, 程慧¹, 江帆², 沈敏¹, 王广海²

作者信息 +

Assessment and treatment for sleep disorders in children with autism spectrum disorder

CHEN Cen^*, CHENG Hui, JIANG Fan, SHEN Min, WANG Guang-hai

Author information +

文章历史 +

摘要

睡眠障碍是孤独症谱系障碍(ASD)儿童最常见的共患障碍之一,不仅与ASD儿童核心症状存在显著相关,还会影响患儿的功能水平、生活质量以及干预康复效果,给父母造成巨大养育压力和经济负担。国际上已将睡眠障碍,特别是失眠纳入到ASD的综合诊治之中,但国内相关工作开展滞后,儿科专业人员对ASD儿童睡眠障碍的诊治能力有待提升。因此,本研究将介绍ASD儿童睡眠障碍的评估和干预方法,为临床和研究工作提供依据。

Abstract

Sleep disorders, as one of the most common comorbid disorders in children with autism spectrum disorder (ASD), have attracted extensive clinical and research attention in recent years.Sleep disorders are significantly related to the core symptoms of ASD, affect the children's function, quality of life and efficacy of intervention and rehabilitation, and also cause great parenting distress and economic burden on parents.At the international level, sleep disorders especially for insomnia have been integrated in the assessment and treatment for ASD, yet the relevant work in China is much less developed and pediatric professionals has insufficient ability to assess and treat sleep disorders in ASD children.Therefore, this review introduces the assessment and treatment strategies for sleep disorders in ASD children in order to inform clinical and research work.

导出引用

陈岑, 程慧, 江帆, 沈敏, 王广海. 孤独症谱系障碍儿童睡眠障碍的评估和干预[J]. 中国儿童保健杂志. 2022, 30(6): 637-641 https://doi.org/10.11852/zgetbjzz2021-0195

CHEN Cen, CHENG Hui, JIANG Fan, SHEN Min, WANG Guang-hai. Assessment and treatment for sleep disorders in children with autism spectrum disorder[J]. Chinese Journal of Child Health Care. 2022, 30(6): 637-641 https://doi.org/10.11852/zgetbjzz2021-0195

中图分类号： R749.94 R740

参考文献

[1] Lord C, Bishop SL.Recent advances in autism research as reflected in DSM-5 criteria for autism spectrum disorder[J].Annu Rev Clin Psychol, 2015, 11:53-70.
[2] Mindell J, Owens JA clinical guide to pediatric sleep diagnosis and management of sleep problems [M].3rd ed.China Lippincott, Williams & Wilkins, 2015:65-95.
[3] Davidl GA,Geraldine D,Daniel HG.Sleep Problems.Autism Spectrum Disorders[M].New York:Oxford University Press, 2010:431-444.
[4] Wang GH, Liu ZJ,Xu GX, et al.Sleep disturbances and associated factors in chinese children with autism spectrum disorder:A retrospective and cross-sectional study[J].Child Psychiatry Human Dev, 2016,47(2):248-258.
[5] 王广海,徐光兴,孙越异,等.自闭症谱系障碍儿童睡眠问题与情绪行为问题的相关研究[J].中国特殊教育,2014(11):53-57.
[6] Levin A,Scher A.Sleep problems in young children with autism spectrum disorders:A study of parenting stress, mothers' sleep-related cognitions, and bedtime behaviors[J].CNS Neurosci Ther, 2016,22(11):921-927.
[7] Kelmanson IA.Sleep disturbances and their associations with emotional/behavioural problems in 5-year-old boys with autism spectrum disorders[J].Early Child Dev Care, 2020,190(2):236-251.
[8] Nguyen AKD, Murphy LE,Kocak M, et al.Prospective associations between infant sleep at 12 months and autism spectrum disorder screening scores at 24 months in a community-based birth cohort[J].Clin Psychiatry, 2018,79(1):16m11127.
[9] Sikora DM, Johnson K, Clemons T, et al.The relationship between sleep problems and daytime behavior in children of different ages with autism spectrum disorders[J].Pediatrics, 2012,130 (Suppl 2):83-90.
[10] Excellence NIfHaC.Autism spectrum disorder in under 19s: support and management[EB/OL].(2020-02-08)https://www.nice.org.uk/guidance/cg170/chapter/1-Recommendations#interventions-for-behaviour-that-challenges.
[11] Cortese S, Wang F, Angriman M, et al.Sleep disorders in children and adolescents with autism spectrum disorder:Diagnosis, epidemiology, and management[J].CNS Drug,2020, 34:415-423.
[12] 中国睡眠研究会.中国失眠障碍诊断和治疗指南[J].中华医学杂志,2017,97(24):1844
[13] 中华人民共和国国家卫生健康委员会.0岁~5岁儿童睡眠卫生指南[EB/OL].(2017-10-12)http://www.moh.gov.cn/zhuz/pqt/201710/e63c5fc4c3d74daf9f5234150c4f400a.shtml
[14] 孙帆,曹牧青,静进.孤独症谱系障碍患儿睡眠问题研究进展[J].中华儿科杂志,2018,56(10):790-793
[15] 侯婷婷,张婷.家长执行的自闭症儿童睡眠障碍干预研究综述[J].中国特殊教育,2018,25(5):33-38.
[16] 黄丹丹,姜志梅,刘洋,等.孤独症谱系障碍儿童共患睡眠障碍相关危险因素的研究进展[J].中国儿童保健杂志,2018,26(7):744-747.
[17] 李小钧,李雪,刘建丛,等.孤独症儿童睡眠问题及其相关因素[J].中国心理卫生杂志,2018,32(1):30-36.
[18] Katz T,Malow B.孤独症谱系障碍儿童睡眠问题实用指南[M].王广海,鲁明辉,译.北京:华夏出版社,2017.
[19] 王广海, 邓玉娇, 姜艳蕊, 等.重视神经发育障碍儿童睡眠障碍[J].中国实用儿科杂志, 2016,31(10):730-734.
[20] Kylan ST,Cynthia RJ.Behavioral interventions to address sleep disturbances in children with autism spectrum disorders:A review[J].Top Early Child Spec,2013,33(3):144-152.
[21] Danelle H, Andrea MN,Chares D,et al.Methods for assessing sleep in children with autism spectrum disorders: A review[J].Res Autism Spect Dis, 2012(6):1337-1344.
[22] Oshua R,Thomas F.Borederline personality pathology, polysomnography, and self -reported sleep problems:A review[J].Curr Sleep Medcine Rep,2015,(1):141-149.
[23] Owens JA,Spirito A, McGuinn M.The Children's Sleep Habits Questionnaire (CSHQ):Psychometric properties of a survey instrument for school-aged children[J].Sleep,2000,23 (8):1043-1051.
[24] Azmeh S, Kate W, Shai M, et al.Children's Sleep Habits Questionnaire (CSHQ)[M]//Shahid A,Wilkinson, K,Marcu S,et al.STOP, THAT and one hundred other sleep scales. New York Springer, 2011.
[25] 李生慧, 金星明, 沈晓明,等.儿童睡眠习惯问卷中文版制定及测量性能考核[J].中华儿科杂志, 2007,45(3):176-180.
[26] Katz T,Shui AM, Johnson CR,et al.Modification of the children's Sleep Habits Questionnaire for Children with Autism Spectrum Disorder[J].J Autism Dev Disord, 2018, 48(8):2629-2641.
[27] Malow BA, Connolly HV, Weiss SK, et al.The Pediatric Sleep Clinical Global Impressions Scale-A new tool to measure pediatric insomnia in autism spectrum disorders[J].J Dev Behav Pediatr, 2016, 37(5):370-376.
[28] Malow BA, Crowe C, Henderson L, et al.A sleep habits questionnaire for children with autism spectrum disorders[J].J Child Neurol, 2009, 24(1):19-24.
[29] Reed HE, McGrew SG,Artibee K,et al.Parent-based sleep education workshops in autism[J].J Child Neurol, 2009, 24(8):936-945.
[30] Devnani PA, Hegde AU.Autism and sleep disorders[J].J Pediatr Neurosci, 2015, 10(4):304-307.
[31] Köse S, Yilmaz H, Ocakoĝlu FT, et al.Sleep problems in children with autism spectrum disorder and intellectual disability without autism spectrum disorder[J].Sleep Med, 2017, 40:69-77.
[32] Cuomo BM,Vaz S, Lee EAL, et al.Effectiveness of sleep-based interventions for children with autism spectrum disorder:A Meta-synthesis[J].Pharmacotherapy, 2017, 37(5):555-578.
[33] Abel EA,Schwichtenberg AJ, Brodhead MT, et al.Sleep and challenging behaviors in the context of intensive behavioral intervention for children with autism[J].J Autism Dev Disord, 2018, 48:3871-3884.
[34] Souders MC, Zavodny S, Eriksen W, et al.Sleep in children with autism spectrum disorder[J].Curr Psychiatry Rep, 2017, 19(6):34.
[35] Turner KS, Johnson CR.Behavioral interventions to address sleep disturbances in children with autism spectrum disorders:A review[J].Top Early Child Spec, 2013, 33(3):144-52.
[36] Williams PG, Sears LL, Allard AM .Sleep problems in children with autism[J].J Sleep Res, 2010, 13(3):265-268.
[37] Mazurek MO, Engelhardt, CR,Hilgard J,et al.Bedtime electronic media use and sleep in children with autism spectrum disorder[J].J Dev Behav Pediatr, 2016, 37(7):525-531.
[38] Ann SS, Kuhn BR, Kennedy AE.Outcomes of a behavioral intervention for sleep disturbances in children with autism spectrum disorder[J].J Autism Dev Disord, 2018, 48:4250-4277.
[39] Kylan ST,Cynthia RJ.Behavioral interventions to address sleep disturbances in children with autism spectrum disorders:A review [J].Top Early Child Spec, 2013, 33(3):144-152.
[40] Jennifer L, Penny V.Behavioral interventions for sleep problems in children with autism spectrum disorders:Current findings and future directions[J].J Pediatr Psychol, 2011, 36(9):1017-1029.
[41] Vriend JL, Corkum PV, Moon EC, et al.Behavioral interventions for sleep problems in children with autism spectrum disorders: Current findings and future directions[J].J Pediatr Psychol, 2011, 6(9):1017-29.
[42] Relia S, Ekambaram V.Pharmacological approach to sleep disturbances in autism spectrum disorders with psychiatric comorbidities:A literature review[J].Med Sci (Basel),2018, 6(4):E95.
[43] Rossignol DA, Frye RE.Melatonin in autism spectrum disorders: A systematic review and meta-analysis[J].Dev Med Child Neurol, 2011, 53:783-792.
[44] Erland LA, Saxena PK.Melatonin natural health products and supplements:Presence of serotonin and significant variability of melatonin content[J].J Clin Sleep Med, 2017, 13: 275-281.
[45] Narasingharao K, Pradhan B, Navaneetham J.Efficacy of structured Yoga intervention for sleep gastrointestinal and behaviour problems of ASD children:An exploratory study[J].J Clin Diagn Res, 2017, 11(3):VC01-VC06.