目的 分析学龄前期癫痫患儿的睡眠状况,探讨其睡眠问题的发生及影响因素。方法 收集2018年6月—2019年6月就诊于西安交通大学第二附属医院儿科的3~5岁癫痫患儿96例作为癫痫组,同时选取年龄、性别与之匹配的健康儿童97例作为对照组。通过对其监护人的询问,运用儿童睡眠习惯问卷(CSHQ)对其睡眠状况进行调查分析,CSHQ总分超过54分即为睡眠质量不良。对可能导致癫痫患儿发生睡眠质量不良的相关因素进行单因素和多因素Logistic回归分析。 结果 1)癫痫组睡眠质量不良发生率高于对照组(33.33% vs. 10.20%,χ2=15.02,P<0.001)。2)癫痫组单因素分析显示:发作类型(χ2=7.200,P=0.007)、发作频率(χ2=14.189,P=0.001)及发作时相(χ2=6.667,P =0.036)可能与其睡眠质量不良的发生相关。3)癫痫组多因素分析结果显示:全面性发作(OR=4.996)、发作集中于睡眠时段(OR=4.320)及发作≥4次/月(OR=7.740)是癫痫患儿睡眠质量不良的危险因素(P<0.05)。 结论 与正常学龄前期儿童相比,癫痫患儿睡眠时长更短,且更容易出现睡眠问题,应对相关问题及早进行识别、干预。
Abstract
Objective To analyze the sleep status of preschool children with epilepsy,and to explore the prevalence and influencing factors of the sleep problems. Methods From June 2018 to June 2019,a total of 96 children with epilepsy aged 3 to 5 in the Department of Pediatrics of the Second Affiliated Hospital of Xi'an Jiaotong University were selected as the epilepsy group,and 97 healthy children matched by age and gender were as controls. The Children's Sleep Habits Questionnaire (CSHQ) was used to investigate and analyze their sleep status,and the total score of CSHQ over 54 points was considered as poor sleep quality. Univariate analysis and Logistic regression analysis were used to determine the related factors that may lead to poor sleep quality in children with epilepsy. Results 1) The incidence of poor sleep quality in epilepsy group was higher than that in control group (33.33% vs. 10.20%,P＜0.001). 2) Univariate analysis showed that seizure types (χ2=7.200,P=0.007),seizure frequency (χ2=14.189,P=0.001) and the time periods of seizure(χ2=6.667,P =0.036)may relate to the occurrence of poor sleep quality. 3) Logistic regression analysis showed that generalized seizure (OR=4.996),seizures concentrated in the sleep period (OR=4.320),frequency≥4 times/month (OR=7.740) were risk factors for poor sleep quality in children with epilepsy. Conclusions Children with epilepsy have shorter sleep duration,and are more likely to have sleep problems than normal preschoolers. It is supposed to give early identification and intervention for epilepsy children with high-risk factors for poor sleep quality.
关键词
癫痫 /
睡眠障碍 /
学龄前儿童
Key words
epilepsy /
sleep disorders /
preschool children
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基金
陕西省软科学研究计划项目(2020KRM060)
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