目的 分析母乳喂养质量改进对极/超低出生体重儿的影响,为对极/超低出生体重儿救治提供有效措施。方法 以本院2018年1月—2019年12月出生且收治入院、出生体重<1 500g的160例早产儿为研究对象,以2019年为干预年,2018年收治的87例新生儿为对照组,2019年收治的73例新生儿为干预组,采用母乳喂养质量改进措施,分析两组患儿质量改进评价指标情况。结果 干预组开始泵奶的时间、禁食次数、禁食天数、静脉营养的时间均少于对照组,差异有统计学意义(t=2.007、2.666、2.222、3.187,P<0.05),两组泌乳开始时间、平均每日泵奶次数、第一次亲母母乳喂养时间、住院期间亲母母乳量、开始喂养时间、微量喂养持续时间、达到全肠道喂养的时间比较,差异均无统计学意义(P>0.05)。干预组喂养不耐受、支气管肺发育不良发生率低于对照组,差异有统计学意义(χ2=4.368、3.963,P<0.05)。干预组与对照组间新生儿坏死性小肠结肠炎、败血症、新生儿胆汁淤积综合症发生率比较差异均无统计学意义(P>0.05)。结论 母乳喂养质量改进可以缩短开始泵奶及静脉营养持续的时间,减少禁食次数、禁食天数,降低喂养不耐受、支气管肺发育不良发生率,为临床救治极/超低出生体重儿提供有效措施。
Abstract
Objective To analyze the effect of breastfeeding quality improvement on in very/extremely low birth weight infants, so as to provide effective measures for clinicians. Methods Totally 160 very/extremely low birth weight infants admitted in Wuxi Maternity and Child Health Care Hospital during January 2018 to December 2019 were analyzed. Newborns admitted in 2018 were selected into the control group, while those admitted in 2019 were enrolled in the intervention group receiving breastfeeding quality improvement measures. Feeding indexes were compared between the two groups. Results The onset time for pumping milk, fasting times, fasting days and intravenous nutrition time in intervention group were shorter than those in control group(t=2.007, 2.666, 2.222, 3.187, P<0.05). But there were no significant differences in the lactation start time, the average daily number of milk pumps, the first breastfeeding time, the amount of mother's breast milk during hospitalization, the starting time of feeding, the duration of micro feeding, and the time for reaching full enteral feeding between the two groups(P>0.05). The rates of feeding intolerance and bronchopulmonary dysplasia in the intervention group were significantly higher than that in control group (χ2=4.368, 3.963, P<0.05), but the differences were not significant on the rates of neonatal necrotizing enterocolitis, sepsis and neonatal cholestasis syndrome(P>0.05). Conclusion The improvement of breastfeeding quality can shorten the time of starting to pump milk and intravenous nutrition, reduce the times and days of fasting, reduce the incidence of feeding intolerance and bronchopulmonary dysplasia, which can provide effective measures for clinicians to treat very/extremely low birth weight infants.
关键词
母乳喂养 /
质量改进 /
极/超低出生体重儿
Key words
breastfeeding /
quality improvement /
very/extremely low birth weight infants
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参考文献
[1] 王丹华. 呵护早产儿从母乳喂养开始[J]. 临床儿科杂志, 2012,30(3):201-203.
[2] 韩树萍. 母乳喂养对新生儿重症监护病房早产儿的益处[J]. 中国新生儿科杂志, 2015,30(3):161-163.
[3] Corpeleijn WE, Kouwenhoven SM, Paap MC, et al. Intake of own mother's milk during the first days of life is associated with decreased morbidity and mortality in very low birth weight infants during the first 60 days of life[J]. Neonatology, 2012,102(4):276-281.
[4] 早产儿营养调查协作组. 新生儿重症监护病房中早产儿营养相关状况多中心调查974例报告[J]. 中华儿科杂志, 2009,47(1):12-17.
[5] Johnston M, Landers S, Noble L, et al. Breastfeeding and the use of human milk[J].Pediatrics,2012,129:e827-e841.
[6] Lee HC, Kurtin PS, Wight NE, et al. A quality improvement project to increase breast milk use in very low birth weight infants[J]. Pediatrics,2012,130:e1679-e1687.
[7] Zhou Q, Zhang L, Lee SK,et al.A quality improvement initiative to increase mother's own milk use in a Chinese neonatal intensive care unit[J].Breastfeed Med,2020,15(4):261-267.
[8] 胥焕, 杨春燕, 许平. 出生体重<1 500 g早产儿静脉营养疗效及并发症观察 [J]. 中华危重病急救医学,2019,31 (11): 1395-1400.
[9] Mangili G, Garzoli E. Feeding of preterm infants and fortification of breast milk[J]. Pediatr Med Chir,2017,39(2):158.
[10] Boer C,Gaal B, Fusch C.Guidelines for feeding very low birth weight infants[J]. Nutrients, 2015,7(1):423-442.
[11] Parker MG, Patel AL.Using quality improvement to increase human milk use for preterm infants[J]. Semin Perinatol,2017,41(3):175-186.
[12] Thakur A,Kler N, Garg P,et al.Impact of quality improvement program on expressed breastmilk usage in very low birth weight infants[J].Indian Pediatr,2018,55(9):739-743.
[13] 凌聪,张静.母乳喂养困难、离乳原因及影响因素的系统综述[J]. 中国儿童保健杂志,2019,3(27): 269-272.
基金
无锡市科技发展基金项目(WX18IIAN030);南京医科大学科技发展基金项目(NMUB2018250);无锡市妇幼保健院青年医学人才项目(妇党发[2017]20号)