目的 研究汉、回民族间母乳主要成分的差异,为促进母乳喂养、促进婴儿生长发育提供基础数据。方法 本研究于2019年6月—2020年5月期间,招募乳母,收集乳汁,采用母乳成分分析仪进行脂肪、蛋白质、乳糖、干物质的检测,使用滴定法检测母乳钙的水平。使用倾向性得分匹配混杂因素,分析汉、回民族间母乳成分的差异。结果 本研究纳入对象1 030人,其中回族43人。使用倾向性得分匹配后,得到匹配对40对。两组母乳能量、总蛋白质、乳糖、脂肪、钙及干物质含量差异无统计学意义(t=0.832、-0.629、-1.058、0.783、-0.758、1.217,P＞0.05)。在相关分析及调整分娩年龄的偏相关分析中均发现,汉族女性母乳蛋白质水平随哺乳时间显著下降(r=-0.191,r'=-0.193,P＜0.001);而回族母乳未观察上述趋势(P>0.05)。结论 回、汉族乳母调查营养素无显著差异,但从变化趋势看,汉族母乳蛋白质随哺乳时间显著降低。
Abstract
Objective To know about the differences in breast milk composition among Han and Hui nationalities of Chinese females,in order to provide basic data for promoting breastfeeding,growth and development of infants. Methods Lactating women were voluntarily recruited in this study June 2019 to May 2020 and their breast milk was collected. Human Milk Analyzer was used to detect the fat,protein,lactose and dry matter content,while the titration method was used to measure the calcium level. Propensity score was used to match the potential confounders before comparing the breast milk composition between Han and Hui groups. Results Total of 1 030 women were enrolled in this study,of whom 43 were Hui people. After matching by propensity score,40 Han and Hui lactating women were paired. There were no significant differences in breast milk energy,protein,lactose,fat,calcium,dry matter between Han and Hui lactating women(t=0.832,-0.629,-1.058,0.783,-0.758,1.217,P＞0.05). A positive correlation was observed between lactation days and protein only in Han women(r=-0.191,r'=-0.193,P<0.001). But this correlation was not observed in breast milk of Hui women(P＞0.05). Conclusions There were no significant differences in breast milk composition between Han and Hui women. However,breast milk protein significantly decreased in Han lactating women.
关键词
汉族 /
回族 /
母乳营养成分 /
倾向性得分匹配
Key words
the Han nationality /
the Hui nationality /
breast milk nutrients /
propensity score matching
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基金
兰州市卫生健康科技发展项目(2019-030);兰州市科技局人才创新创业项目(2017-RC-18)
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