目的 探讨维生素AD(VAD)在运动发育迟缓患儿康复治疗中的作用,指导临床治疗。方法 选取2018年10月-2019年5月在本院康复中心住院的运动发育迟缓患儿90例,随机分为对照组、维生素D(VD)组和VAD组各30例,治疗前、治疗3 个月后完善维生素A、25-(OH)D、IgA检测,调查住院期间感染情况;采用Peabody运动发育评定量表评定粗大、精细运动能力;采用盖塞尔(Gesell)发育量表评估单项发育商。结果 治疗前,三组患儿维生素A、25-(OH)D均偏低;治疗3个月后,对照组较前降低,VD组维生素A较前降低、25-(OH)D较前提高,VAD组维生素A、25-(OH)D较前均提高;住院期间对照组总感染率为50%,VD组总感染率为33.3%,VAD总感染率为13.3%;三组患儿治疗后粗大、精细运动功能评分、Gesell发育量表评估较前均有所提高,VAD组明显优于VD组和对照组,差异有统计学意义(P<0.05)。结论 对于住院康复治疗的运动发育迟缓患儿,VAD能增强抵抗力,减少康复期间院内感染,提高康复治疗疗效。
Abstract
Objective To analyze the role of vitamin AD in rehabilitation treatment of children with motor retardation,to guide the clinicl diagnesis. Methods Totally 90 children with motor retardation were randomly divided into control group(n=30), VD group(n=30) and VAD group(n=30).Vitamin A,25 hydroxyvitamin D and IgA levels were detected before and 3 months after treatment,Infection status during hospitalization was investigated. Peabody Motor Development Rating Scale was used to evaluate gross and fine motor ability, and Gessel(Gesell) Development Scale was used to evaluate single development quotient. Results Before treatment, vitamin A and 25-(OH)D levels were lower in the three groups.After 3 months of treatment, the levels of vitamin A and 25-(OH)D in the control group were lower than those before treatment, while those in the VD group were lower and 25-(OH)D levels were higher than those before treatment.Vitamin A and 25-(OH)D levels were increased in VAD group.During hospitalization, the total infection rate was 50% in control group,33.3% in VD group and 13.3% in VAD group.The scores of gross and fine motor function and the evaluation of Gesell Development Scale were improved in the three groups after treatment.The score of gross and fine motor function and the evaluation of VAD group were significantly better than those of VD group and control group.Conclusion Vitamin AD can enhance the resistance, reduce nosocomial infection and improve the curative effect of rehabilitation in children with motor retardation.
关键词
维生素AD /
运动发育迟缓 /
康复治疗 /
儿童
Key words
vitamin AD /
exercise retardation /
rehabilitation therapy /
children
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