营养膳食与生命早期发育的表观遗传的认识进展

张霆

doi:10.11852/zgetbjzz2019-0908

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中国儿童保健杂志 ›› 2019, Vol. 27 ›› Issue (7) : 697-700. DOI: 10.11852/zgetbjzz2019-0908

专家笔谈

营养膳食与生命早期发育的表观遗传的认识进展

张霆

作者信息 +

Progress on the epigenetic knowledge of dietary nutrition and the development in early life

ZHANG Ting

Author information +

文章历史 +

摘要

生命早期1 000 天的发育是密切伴随着表观遗传的动态编程与调控,这一过程与儿童的早期膳食平衡密切相关,其体现了体内环境与遗传的交互作用。因此,就生命前沿的表观遗传学进展,本文介绍了将基因组比喻为“计算机硬件系统”和“软件操作系统”的不同功能形象,同时也介绍了“饭碗中的遗传学”(genetics in our food)这一营养表观遗传学的基本概念,强调了从机体膳食营养摄入到细胞内三大生化基本代谢乃至到基因组化学修饰三者密切关联,因此为日常专业的儿童膳食营养均衡指导工作提供更为科学的遗传学和表观遗传学依据。

Abstract

The development in the first thousand days of a child is closely accompanied by epigenetic dynamic programming and regulation. This process is closely related to the early dietary balance of children,which reflects the interaction between body environment and genetics. This paper introduces the functional genome compared to the computer′s hardware system and software operating system,as well as the concept of ′genetics in our food′. Furthermore,the close correlation among body′s dietary nutrition intake,the three biochemical basic metabolism in cells and genomic chemical modification is emphasized in this paper,thereby providing more scientific genetic and epigenetic basis for daily professional guidance on children′s nutrition balance

导出引用

张霆. 营养膳食与生命早期发育的表观遗传的认识进展[J]. 中国儿童保健杂志. 2019, 27(7): 697-700 https://doi.org/10.11852/zgetbjzz2019-0908

ZHANG Ting. Progress on the epigenetic knowledge of dietary nutrition and the development in early life[J]. Chinese Journal of Child Health Care. 2019, 27(7): 697-700 https://doi.org/10.11852/zgetbjzz2019-0908

中图分类号： R725.4 R723.14

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